(R)-(+)-1-Phenyl-1,3-propanediol

Base Information

Chemical Name:(R)-(+)-1-Phenyl-1,3-propanediol
CAS No.:103548-16-9
Molecular Formula:C9H12 O2
Molecular Weight:152.193
Hs Code.:29062900
DSSTox Substance ID:DTXSID90370608
Nikkaji Number:J1.303.135E
Mol file:103548-16-9.mol

Synonyms:103548-16-9;(R)-(+)-1-Phenyl-1,3-propanediol;(R)-1-PHENYL-1,3-PROPANEDIOL;(R)-1-Phenylpropane-1,3-diol;(1R)-1-phenylpropane-1,3-diol;1,3-Propanediol,1-phenyl-, (1R)-;SCHEMBL973028;DTXSID90370608;RRVFYOSEKOTFOG-SECBINFHSA-N;(R)-1-phenyl-1,3-dihydroxypropane;(R)-3-phenyl-1,3-dihydroxypropane;MFCD00145213;AKOS015913707;CS-0329795;C80043;A896419;J-000999;(R)-(+)-1-Phenyl-1,3-propanediol, >=99.0% (sum of enantiomers, GC)

Suppliers and Price of (R)-(+)-1-Phenyl-1,3-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(R)-(+)-1-Phenyl-1,3-propanediol ≥99.0% (sum of enantiomers, GC)
1g
$ 346.00

Crysdot
(R)-1-Phenylpropane-1,3-diol 95+%
1g
$ 376.00

Chemenu
(R)-1-phenylpropane-1,3-diol 95%
1g
$ 355.00

Apolloscientific
(R)-1-Phenyl-1,3-propanediol 95%
1g
$ 718.00

Apolloscientific
(R)-1-Phenyl-1,3-propanediol 95%
250mg
$ 254.00

American Custom Chemicals Corporation
(R)-(+)-1-PHENYL-1,3-PROPANEDIOL 95.00%
1G
$ 308.64

Total 12 raw suppliers

Chemical Property of (R)-(+)-1-Phenyl-1,3-propanediol

Chemical Property:

Vapor Pressure:0.000255mmHg at 25°C
Melting Point:62-66 °C
Refractive Index:1.4910 (estimate)
Boiling Point:310.6°Cat760mmHg
PKA:13.95±0.20(Predicted)
Flash Point:153.9°C
PSA：40.46000
Density:1.131g/cm³
LogP:1.10240
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:152.083729621
Heavy Atom Count:11
Complexity:97.7

Purity/Quality:

97% ^*data from raw suppliers

(R)-(+)-1-Phenyl-1,3-propanediol ≥99.0% (sum of enantiomers, GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CCO)O
Isomeric SMILES:C1=CC=C(C=C1)[C@@H](CCO)O
Uses (1R)-1-Phenyl-1,3-propanediol is used in the synthesis and characterization of cytochrome P450 3A-activated prodrugs which are useful for targeting phosph(on)ate-based drugs to liver. It is also used in the synthesis of 1,3-diols by diarylprolinol-catalyzed aldol reaction of acetaldehyde with aldehydes followed by reduction.

Technology Process of (R)-(+)-1-Phenyl-1,3-propanediol

There total 59 articles about (R)-(+)-1-Phenyl-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%