1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine

Base Information

Chemical Name:1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine
CAS No.:83823-48-7
Molecular Formula:C₂₁H₂₆N₂O₂
Molecular Weight:338.45
Hs Code.:
DSSTox Substance ID:DTXSID601003904

Synonyms:BRN 4530934;1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine;Piperazine, 1-((3,4-dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenyl-;83823-48-7;DTXSID601003904;LS-111658;1-[(8-Methoxy-3,4-dihydro-2H-1-benzopyran-3-yl)methyl]-4-phenylpiperazine

Suppliers and Price of 1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine

Chemical Property:

Vapor Pressure:1.04E-09mmHg at 25°C
Boiling Point:489°Cat760mmHg
Flash Point:141.2°C
Density:1.136g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:338.199428076
Heavy Atom Count:25
Complexity:405

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1OCC(C2)CN3CCN(CC3)C4=CC=CC=C4

Technology Process of 1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine

There total 8 articles about 1-((3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-yl)methyl)-4-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 83823-48-7
1-(8-Methoxy-chroman-3-ylmethyl)-4-phenyl-piperazine

Guidance literature:: Multi-step reaction with 6 steps

1: 1,5-Diazabicyclo<2.2.2>octane / Heating

2: 10percent NaOH / Heating

3: SOCl₂ / benzene / 3 h / Heating

4: Et₃N / benzene

5: LiAlH₄ / diethyl ether / Heating

6: H₂ / 10percent Pd/C / ethanol / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; 1,8-diazabicyclo[2.2.2.]octane; hydrogen; triethylamine; palladium on activated charcoal; In diethyl ether; ethanol; benzene;

Reference yield:

: 83823-41-0
1-(8-Methoxy-2H-chromen-3-ylmethyl)-4-phenyl-piperazine

: 83823-48-7
1-(8-Methoxy-chroman-3-ylmethyl)-4-phenyl-piperazine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Ambient temperature;

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 83823-48-7
1-(8-Methoxy-chroman-3-ylmethyl)-4-phenyl-piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / benzene

2: LiAlH₄ / diethyl ether / Heating

3: H₂ / 10percent Pd/C / ethanol / Ambient temperature

With lithium aluminium tetrahydride; hydrogen; triethylamine; palladium on activated charcoal; In diethyl ether; ethanol; benzene;