(S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine

Base Information

Chemical Name:(S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine
CAS No.:847805-32-7
Molecular Formula:C16H23NO4
Molecular Weight:293.363
Hs Code.:
Mol file:847805-32-7.mol

Synonyms:(S)-4-Boc-2-((S)-hydroxy(phenyl)methyl)morpholine;

Suppliers and Price of (S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine

Chemical Property:

Melting Point:104-105℃
PSA：59.00000
LogP:2.29380

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine

There total 24 articles about (S)-4-Boc-2-((S)-hydroxy(phenyl)Methyl)Morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1239893-05-0
C₂₃H₂₉NO₄

: 847805-32-7
(+)-(2S,3S)-2-[α-hydroxy(phenyl)methyl]morpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 25 ℃; for 12h;
DOI:10.1039/c0cc00650e

Reference yield: 83.0%

: 911061-55-7
C₁₁H₁₅NO₂

: 24424-99-5
di-tert-butyl dicarbonate

: 847805-32-7
(+)-(2S,3S)-2-[α-hydroxy(phenyl)methyl]morpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: With sodium hydroxide; In dichloromethane; water; at 0 - 20 ℃; for 5h;
DOI:10.1055/s-2006-944210

Reference yield: 60.0%

: 108-86-1,52753-63-6
bromobenzene

: 847805-31-6
(S)-(+)-2-formylmorpholine-4-carboxylic acid tert-butyl ester

: 847805-33-8
(+)-(2S,3R)-2-[α-hydroxy(phenyl)methyl]morpholine-4-carboxylic acid tert-butyl ester

: 847805-32-7
(+)-(2S,3S)-2-[α-hydroxy(phenyl)methyl]morpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: bromobenzene; With iodine; magnesium; In tetrahydrofuran; at 20 ℃; for 1h;

(S)-(+)-2-formylmorpholine-4-carboxylic acid tert-butyl ester; With zinc dibromide; In tetrahydrofuran; at 20 ℃; for 18h;
DOI:10.1021/ol050059g