(S)-N-Boc-2-morpholinecarbaldehyde

Base Information

Chemical Name:(S)-N-Boc-2-morpholinecarbaldehyde
CAS No.:847805-31-6
Molecular Formula:C10H17NO4
Molecular Weight:215.249
Hs Code.:2934999090
European Community (EC) Number:857-983-1
DSSTox Substance ID:DTXSID60364019
Wikidata:Q72450109
Mol file:847805-31-6.mol

Synonyms:(S)-N-Boc-2-morpholinecarbaldehyde;847805-31-6;(S)-tert-butyl 2-formylmorpholine-4-carboxylate;Tert-butyl (2S)-2-formylmorpholine-4-carboxylate;tert-butyl (S)-2-formylmorpholine-4-carboxylate;(S)-4-Boc-2-morpholinecarbaldehyde;SCHEMBL5302913;(S)-4-Boc-2-formyl-morpholine;DTXSID60364019;XIB80531;MFCD08752315;(S)-4-Boc-morpholine-2-carbaldehyde;AKOS016002176;CS-0131430;(S)-tert-butyl2-formylmorpholine-4-carboxylate;EN300-6289923;1,1-dimethylethyl (2S)-2-formyl-4-morpholinecarboxylate;Z1505713432;(2S)-2-(Formyl)morpholine-4-carboxylic Acid tert-Butyl Ester

Suppliers and Price of (S)-N-Boc-2-morpholinecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2-(Formyl)morpholine-4-carboxylicAcidtert-ButylEster
10mg
$ 85.00

SynQuest Laboratories
tert-Butyl (2S)-2-formylmorpholine-4-carboxylate
500 mg
$ 624.00

SynQuest Laboratories
tert-Butyl (2S)-2-formylmorpholine-4-carboxylate
1 g
$ 1180.00

Crysdot
(S)-tert-Butyl2-formylmorpholine-4-carboxylate 97%
1g
$ 396.00

Chemenu
tert-butyl(S)-2-formylmorpholine-4-carboxylate 97%
1g
$ 371.00

American Custom Chemicals Corporation
(S)-4-BOC-2-MORPHOLINECARBALDEHYDE 95.00%
250MG
$ 825.00

American Custom Chemicals Corporation
(S)-4-BOC-2-MORPHOLINECARBALDEHYDE 95.00%
5MG
$ 437.50

Alichem
(S)-tert-Butyl2-formylmorpholine-4-carboxylate
250mg
$ 312.90

Alichem
(S)-tert-Butyl2-formylmorpholine-4-carboxylate
1g
$ 744.00

Activate Scientific
(S)-4-Boc-morpholine-2-carbaldehyde 95+% ee
1 g
$ 594.00

Total 16 raw suppliers

Chemical Property of (S)-N-Boc-2-morpholinecarbaldehyde

Chemical Property:

Vapor Pressure:0.000655mmHg at 25°C
Boiling Point:309.1oC at 760 mmHg
Flash Point:140.7oC
PSA：55.84000
Density:1.18g/cm3
LogP:0.75910
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:215.11575802
Heavy Atom Count:15
Complexity:246

Purity/Quality:

97% ^*data from raw suppliers

(2S)-2-(Formyl)morpholine-4-carboxylicAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCOC(C1)C=O
Isomeric SMILES:CC(C)(C)OC(=O)N1CCO[C@@H](C1)C=O
Uses (2S)-2-(Formyl)morpholine-4-carboxylic Acid tert-Butyl Ester is a zwitterionic chemokine receptors, CCR3 antagonists with selectivity and outstanding pharmacokinetics for potential allergy treatment.

Technology Process of (S)-N-Boc-2-morpholinecarbaldehyde

There total 7 articles about (S)-N-Boc-2-morpholinecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 135065-76-8
tert-butyl (2S)-2-(hydroxymethyl)morpholine-4-carboxylate

: 847805-31-6
(S)-(+)-2-formylmorpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; trichloroisocyanuric acid; sodium hydrogencarbonate; In ethyl acetate; at -5 ℃; for 2h;
DOI:10.1021/ol050059g

Reference yield:

: 132073-83-7
(S)-morpholin-2-ylmethanol

: 847805-31-6
(S)-(+)-2-formylmorpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH

2: trichloroisocyanuric acid; TEMPO; NaHCO₃

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hydroxide; trichloroisocyanuric acid; sodium hydrogencarbonate;
DOI:10.1016/j.bmcl.2006.10.018

Reference yield:

: 847805-30-5
(6S)-6-(hydroxymethyl)morpholin-3-one

: 847805-31-6
(S)-(+)-2-formylmorpholine-4-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: red-Al / tetrahydrofuran

2: NaOH

3: trichloroisocyanuric acid; TEMPO; NaHCO₃

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hydroxide; trichloroisocyanuric acid; sodium hydrogencarbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2006.10.018