6-Methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile

Base Information

• Chemical Name: 6-Methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile
• CAS No.: 849549-26-4
• Molecular Formula: C17H12N2O2
• Molecular Weight: 276.294
• DSSTox Substance ID: DTXSID80459911
• Wikidata: Q82283796

Synonyms:849549-26-4;6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile;SCHEMBL3116031;DTXSID80459911;TVUAYFVGQJIYGX-UHFFFAOYSA-N;FT-0709624

Chemical Property of 6-Methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 276.089877630
• Heavy Atom Count: 21
• Complexity: 496

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)C(=O)NC(=C2C3=CC=CC=C3)C#N

Technology Process of 6-Methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile

There total 1 articles about 6-Methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-allyl-6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile (849634-85-1) + formic acid (64-18-6) → 6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile (849549-26-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In 1,4-dioxane; at 100 ℃; for 1.5h;

Reference yield:

6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile (849549-26-4) → 3-(aminomethyl)-6-methoxy-4-phenylisoquinolin-1(2H)-one (849548-88-5)

Guidance literature:

With ammonia; hydrogen; nickel; In methanol; ethanol; under 2585.81 Torr;

Reference yield:

glycidyl isopropyl ether (4016-14-2) + 6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile (849549-26-4) → 2-(2-hydroxy-3-isopropoxypropyl)-6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile (849634-94-2)

Guidance literature:

With pyridine; In isopropyl alcohol; at 20 ℃; Heating / reflux;

upstream raw materials:

2-allyl-6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile

formic acid

Downstream raw materials:

1-chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile

6-methoxy-4-phenylisoquinoline-1,3-dicarbonitrile

3-cyano-6-methoxy-4-phenylisoquinoline-1-carboxylic acid

1-{[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}-6-methoxy-4-phenylisoquinoline-3-carbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 849549-26-4 3-Isoquinolinecarbonitrile, 1,2-dihydro-6-methoxy-1-oxo-4-phenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send