Benzoic acid, 3-methoxy-, 2-acetylphenyl ester

Base Information

• Chemical Name: Benzoic acid, 3-methoxy-, 2-acetylphenyl ester
• CAS No.: 85079-06-7
• Molecular Formula: C16H14O4
• Molecular Weight: 270.285
• Mol file: 85079-06-7.mol

Synonyms:

Chemical Property of Benzoic acid, 3-methoxy-, 2-acetylphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 3-methoxy-, 2-acetylphenyl ester

There total 4 articles about Benzoic acid, 3-methoxy-, 2-acetylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-methoxystyrene (626-20-0) + o-hydroxyacetophenone (118-93-4,104809-67-8) → 2-<(3-methoxybenzoyl)oxy>acetophenone (85079-06-7)

Guidance literature:

With tert.-butylhydroperoxide; copper diacetate; In acetonitrile; at 80 ℃; for 15h;

DOI:10.1016/j.tet.2021.132000

Reference yield:

o-hydroxyacetophenone (118-93-4,104809-67-8) + m-anisoyl chloride (1711-05-3) → 2-<(3-methoxybenzoyl)oxy>acetophenone (85079-06-7)

Guidance literature:

With pyridine;

DOI:10.1016/j.bmc.2006.03.031

Reference yield:

3-Methoxybenzoic acid (586-38-9) → 2-<(3-methoxybenzoyl)oxy>acetophenone (85079-06-7)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 2 h / Ambient temperature

2: pyridine / 0.75 h / 0 - 20 °C

With pyridine; oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00025a011

upstream raw materials:

o-hydroxyacetophenone

m-anisoyl chloride

3-Methoxybenzoic acid

Phenyl acetate

Downstream raw materials:

2-(3-methoxyphenyl)-3-methylbenzofuran

1-(2-hydroxyphenyl)-3-(3-methoxyphenyl)-1,3-propanedione

3'-methoxy-4-thioflavone

3'-methoxyflavone