N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide

Base Information

• Chemical Name: N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide
• CAS No.: 54797-23-8
• Molecular Formula: C16H15NO2
• Molecular Weight: 253.301
• Hs Code.: 2924299090
• Nikkaji Number: J13.109A
• Mol file: 54797-23-8.mol

Synonyms:UTILAMIDE;N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide;54797-23-8;Alatamide;N-[(E)-4-Methoxystyryl]benzamide;SCHEMBL19435704;AMY36845

Chemical Property of N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide

Chemical Property:

• Vapor Pressure: 2.12E-09mmHg at 25°C
• Boiling Point: 480.7°Cat760mmHg
• Flash Point: 244.5°C
• PSA: 41.82000
• Density: 1.137g/cm³
• LogP: 3.67070
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 253.110278721
• Heavy Atom Count: 19
• Complexity: 300

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=CNC(=O)C2=CC=CC=C2
• Isomeric SMILES: COC1=CC=C(C=C1)/C=C/NC(=O)C2=CC=CC=C2

Technology Process of N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide

There total 20 articles about N-[(E)-2-(4-methoxyphenyl)ethenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzoic acid anhydride (93-97-0) + 1-azido-2-(4-methoxyphenyl)ethane (74447-44-2) → trans-N-[2-(4-Methoxy-phenyl)-vinyl]-benzamide (54797-23-8)

Guidance literature:

With di[(2,4-bis-tert-butyl-1-methoxy-3-neopentylcyclopentadienyl)dichlororuthenium(III)]; triethylamine; 1-methyl-3-octylimidazol-3-ium chloride; at 70 ℃; for 3h; Inert atmosphere;

DOI:10.1002/cctc.201500935

Reference yield: 91.0%

N-(pivaloyloxy)benzamide (61650-22-4) + (E)-2-(4-methoxyphenyl)vinylboronic acid (72316-18-8) → trans-N-[2-(4-Methoxy-phenyl)-vinyl]-benzamide (54797-23-8)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; In methanol; at 20 ℃; for 12h; Mechanism;

DOI:10.1021/ol501309e

Reference yield: 90.0%

(Z)-N-(2-bromo-2-(4-methoxyphenyl)vinyl)benzamide → trans-N-[2-(4-Methoxy-phenyl)-vinyl]-benzamide (54797-23-8)

Guidance literature:

With acetic acid; In tetrahydrofuran; methanol; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.09.008

upstream raw materials:

(Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester

(1-(4-methoxyphenyl)-2-nitroethyl) phenyl sulfide

2-(p-methoxyphenyl)-2-(phenylthio)-1-aminoethane

4-methoxy-benzaldehyde

Downstream raw materials:

5-(4-methoxyphenyl)-2-phenyl-1,3-oxazole