(Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester

Base Information

• Chemical Name: (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester
• CAS No.: 75437-11-5
• Molecular Formula: C₁₈H₁₇NO₄
• Molecular Weight: 311.337
• Mol file: 75437-11-5.mol

Synonyms:(Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester

Chemical Property of (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester

There total 10 articles about (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methanol (67-56-1) + (4Z)-4-(4-methoxybenzylidene)-2-phenyl-oxazolin-5-one (57427-78-8) → (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester (75437-11-5)

Guidance literature:

With mercury(II) diacetate; at 70 ℃;

DOI:10.1080/00397911.2010.523157

Reference yield: 82.0%

Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) + methanol (67-56-1) + 4-methoxy-benzaldehyde (123-11-5) → (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester (75437-11-5)

Guidance literature:

Hippuric Acid; With chloroformic acid ethyl ester; triethylamine; In benzene; at 0 - 20 ℃;

4-methoxy-benzaldehyde; In benzene; at 80 ℃; for 2h;

methanol; With triethylamine; at 65 ℃; for 3h;

DOI:10.1039/d0ob00557f

Reference yield: 45.0%

(4Z)-4-(4-methoxybenzylidene)-2-phenyl-oxazolin-5-one (57427-78-8) + methoxybenzene (100-66-3) → (Z)-N-benzoylamino-3-(4-methyoxyphenyl) acrylic acid methyl ester (75437-11-5)

Guidance literature:

With potassium hydroxide; In benzene; at 40 ℃; ultrasound irradiation;

upstream raw materials:

(4Z)-4-(4-methoxybenzylidene)-2-phenyl-oxazolin-5-one

methanol

methoxybenzene

diazomethane

Downstream raw materials:

trans-N-[2-(4-Methoxy-phenyl)-vinyl]-benzamide

(R)-4-methoxy-N-benzoyl-phenylalanine-methylester

(S)-4-methoxy-N-benzoyl-phenylalanine-methylester

methyl Z-2-benzamido-3-p-methoxyphenyl-2-butanoate