6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid

Base Information

Chemical Name:6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid
CAS No.:85870-50-4
Molecular Formula:C₁₀H₈N₂O₃
Molecular Weight:204.185
Hs Code.:2933790090
DSSTox Substance ID:DTXSID80518294
Wikidata:Q82380890
Mol file:85870-50-4.mol

Synonyms:85870-50-4;6-amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid;6-AMINO-2-OXO-1H-QUINOLINE-3-CARBOXYLIC ACID;6-Amino-2-hydroxyquinoline-3-carboxylic acid;6-amino-1,2-dihydro-2-oxo-3-quinolinecarboxylic acid;SCHEMBL11142199;DTXSID80518294;DIOKGSRWVHKXED-UHFFFAOYSA-N

Suppliers and Price of 6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid

Chemical Property:

Boiling Point:534.6±50.0 °C(Predicted)
PKA:1.77±0.20(Predicted)
PSA：96.18000
Density:1.516±0.06 g/cm3(Predicted)
LogP:1.38970
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.05349212
Heavy Atom Count:15
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1N)C=C(C(=O)N2)C(=O)O

Technology Process of 6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid

There total 7 articles about 6-Amino-2-oxo-1,2-dihydroquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85870-49-1
1,2-dihydro-6-nitro-2-oxo-3-quinolinecarboxylic acid

: 85870-50-4
6-amino-1,2-dihydro-2-oxo-3-quinolinecarboxylic acid

Guidance literature:: With hydrogen; nickel; In N,N-dimethyl-formamide;

Reference yield:

: 17422-56-9
diethyl 2-(2-nitrobenzylidene)malonate

: 85870-50-4
6-amino-1,2-dihydro-2-oxo-3-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 48.5 g / H₂ / Raney Ni / ethanol

2: 10.7 g / 96percent H₂SO₄, 70percent HNO₃ / 1 h / 0 °C

3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating

4: 18.3 g / H₂ / Raney Ni / dimethylformamide

With hydrogenchloride; sodium hydroxide; sulfuric acid; hydrogen; nitric acid; nickel; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 91538-60-2
N-(2-formyl-4-nitrophenyl)acetamide

: 85870-50-4
6-amino-1,2-dihydro-2-oxo-3-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 0.92 g / aq. HCl / 1.5 h / Heating

2: 0.18 g / 17.5 h / 150 - 160 °C

3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating

4: 18.3 g / H₂ / Raney Ni / dimethylformamide

With hydrogenchloride; sodium hydroxide; hydrogen; nickel; In hydrogenchloride; N,N-dimethyl-formamide;