2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine

Base Information

• Chemical Name: 2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine
• CAS No.: 38965-47-8
• Molecular Formula: C9H10N4
• Molecular Weight: 174.2
• Hs Code.: 2933990090
• Mol file: 38965-47-8.mol

Synonyms:2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine;1-METHYL-3-(PYRIDIN-4-YL)-1H-PYRAZOL-5-AMINE;

Chemical Property of 2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine

Chemical Property:

• PSA: 56.73000
• LogP: 1.64550
• Storage Temp.: 2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine

There total 6 articles about 2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

3-oxo-3-(pyridin-4-yl)propanenitrile (23821-37-6) + methylhydrazine (60-34-4) → 1-methyl-5-(pyridin-4-yl)-1H-pyrazol-3-amine (1240522-04-6) + 1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine (38965-47-8)

Guidance literature:

In methanol; at 60 ℃; for 2.5h;

Reference yield: 71.0%

3-oxo-3-(pyridin-4-yl)propanenitrile (23821-37-6) + methylhydrazine (60-34-4) → 1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine (38965-47-8)

Guidance literature:

With hydrogenchloride; In methanol; at 60 ℃; for 2.5h;

DOI:10.1021/ml4000854

Reference yield: 60.0%

5-bromo-2-methyl-2H-pyrazol-3-ylamine (1357471-14-7) + 4-pyridineboronic acid pinacol ester (181219-01-2) → 1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine (38965-47-8)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane; water; at 120 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;

upstream raw materials:

3-oxo-3-(pyridin-4-yl)propanenitrile

methylhydrazine

5-bromo-2-methyl-2H-pyrazol-3-ylamine

4-pyridineboronic acid pinacol ester

Downstream raw materials:

C₃₃H₂₉N₅O₃

C₂₃H₂₇N₅O₃

(S)-2-((1-((1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)acetic acid

(S)-tert-butyl 1-(1-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-ylamino)-1-oxo-3-phenylpropan-2-ylcarbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 38965-47-8 2-Methyl-5-pyridin-4-yl-2H-pyrazol-3-ylamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send