5-Bromo-2-isopropylisoindolin-1-one

Base Information

Chemical Name:5-Bromo-2-isopropylisoindolin-1-one
CAS No.:864866-47-7
Molecular Formula:C11H12BrNO
Molecular Weight:254.126
Hs Code.:2933790090
DSSTox Substance ID:DTXSID90470950
Mol file:864866-47-7.mol

Synonyms:5-BROMO-2-ISOPROPYLISOINDOLIN-1-ONE;864866-47-7;5-bromo-2-propan-2-yl-3H-isoindol-1-one;5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one;SCHEMBL1500196;DTXSID90470950;LWLIXVFOQPOESZ-UHFFFAOYSA-N;MFCD12400939;AKOS022178288;SB39148;AS-35572;CS-0171962;EN300-790858;A863157;5-bromo-2-(propan-2-yl)-2,3-dihydro-1H-isoindol-1-one

Suppliers and Price of 5-Bromo-2-isopropylisoindolin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Bromo-2-isopropylisoindolin-1-one 97%
1g
$ 363.00

Chemenu
5-bromo-2-isopropylisoindolin-1-one 95%+
1g
$ 339.00

Alichem
5-Bromo-2-isopropylisoindolin-1-one
1g
$ 506.11

Alichem
5-Bromo-2-isopropylisoindolin-1-one
250mg
$ 207.90

Alichem
5-Bromo-2-isopropylisoindolin-1-one
5g
$ 1474.72

AK Scientific
5-Bromo-2-isopropylisoindolin-1-one
1g
$ 831.00

AK Scientific
5-Bromo-2-isopropylisoindolin-1-one
250mg
$ 311.00

Total 7 raw suppliers

Chemical Property of 5-Bromo-2-isopropylisoindolin-1-one

Chemical Property:

PSA：20.31000
LogP:2.75120
Storage Temp.:2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:253.01023
Heavy Atom Count:14
Complexity:241

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-isopropylisoindolin-1-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1CC2=C(C1=O)C=CC(=C2)Br

Technology Process of 5-Bromo-2-isopropylisoindolin-1-one

There total 9 articles about 5-Bromo-2-isopropylisoindolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 888030-75-9
N-isopropyl-4-bromo-2-hydroxymethylbenzamide

: 888030-82-8
(5-bromo-3H-isobenzofuran-1-ylidene)-isopropyl-amine

: 864866-47-7
5-bromo-2-(propan-2-yl)-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: N-isopropyl-4-bromo-2-hydroxymethylbenzamide; With isopropylmagnesium chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

With N,N,N',N'-Tetramethylphosphorodiamidic chloride; In tetrahydrofuran; at 20 ℃; for 14h;
DOI:10.1055/s-2006-933114

Reference yield: 80.0%

: 75-31-0
isopropylamine

: 78471-43-9
methyl 4-bromo-2-(bromomethyl)benzoate

: 864866-47-7
5-bromo-2-(propan-2-yl)-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: With triethylamine; In toluene; Reflux;
DOI:10.1016/j.bmcl.2015.01.035

Reference yield: 64.8%

: 888030-75-9
N-isopropyl-4-bromo-2-hydroxymethylbenzamide

: 864866-47-7
5-bromo-2-(propan-2-yl)-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: N-isopropyl-4-bromo-2-hydroxymethylbenzamide; With isopropylmagnesium chloride; In 1,3-dimethyl-2-imidazolidinone; at -10 - 20 ℃;

With diethyl chlorophosphate; In 1,3-dimethyl-2-imidazolidinone; at 0 - 20 ℃;

In n-heptane; isopropyl alcohol; at -6 - 50 ℃;
DOI:10.1021/op900062p