16-methylene estrone

Base Information

Chemical Name:16-methylene estrone
CAS No.:10506-73-7
Molecular Formula:C19H22 O2
Molecular Weight:282.38
Hs Code.:
Mol file:10506-73-7.mol

Synonyms:Estrone,16-methylene- (6CI); 16-Methyleneestrone

Suppliers and Price of 16-methylene estrone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 16-methylene estrone

Chemical Property:

Vapor Pressure:3.42E-09mmHg at 25°C
Boiling Point:463°C at 760 mmHg
Flash Point:197°C
PSA：37.30000
Density:1.18g/cm³
LogP:3.98350

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 16-methylene estrone

There total 4 articles about 16-methylene estrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 64-17-5
ethanol

: 7627-93-2
3-O-acetyl-16-methylene-estrone

: 16β-ethoxymethyl-estrone

: 10506-73-7
3-hydroxy-16-methylen-estra-1,3,5⁽¹⁰⁾-trien-17-one

Guidance literature:: With potassium hydroxide; at 0 ℃; for 0.5h;
DOI:10.1021/jm050830t

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 53-16-7
Estrone

: 10506-73-7
3-hydroxy-16-methylen-estra-1,3,5⁽¹⁰⁾-trien-17-one

Guidance literature:: With potassium hydroxide; In ethanol; water; at 20 ℃; for 24h;
DOI:10.3390/molecules24112054

Reference yield:

: 901-93-9
estrone acetate

: 10506-73-7
3-hydroxy-16-methylen-estra-1,3,5⁽¹⁰⁾-trien-17-one

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / dimethylamine hydrochloride / 3-methyl-butan-1-ol / 24 h / Heating

2: aq. KOH / 0.5 h / 0 °C

With potassium hydroxide; N,N-dimethylammonium chloride; In i-Amyl alcohol;
DOI:10.1021/jm050830t