2-METHYL-4-OCTANONE

Base Information

• Chemical Name: 2-METHYL-4-OCTANONE
• CAS No.: 7492-38-8
• Molecular Formula: C9H18O
• Molecular Weight: 142.241
• Hs Code.: 2914190090
• Mol file: 7492-38-8.mol

Synonyms:4-Octanone, 2-methyl-;

Chemical Property of 2-METHYL-4-OCTANONE

Chemical Property:

• Vapor Pressure: 0.913mmHg at 25°C
• Melting Point: -18.52°C (estimate)
• Refractive Index: 1.415
• Boiling Point: 180.042 °C at 760 mmHg
• Flash Point: 57.565 °C
• PSA: 17.07000
• Density: 0.815 g/cm³
• LogP: 2.79180
• Storage Temp.: 2-8°C

Purity/Quality:

99.0% ^*data from raw suppliers

2-Methyloctan-4-one 95+% ^*data from reagent suppliers

Safty Information:

• Statements: 52

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Methyl-4-octanone is a building block ketone for proteomics research. It is also used as pharmaceutical intermediates.

Technology Process of 2-METHYL-4-OCTANONE

There total 16 articles about 2-METHYL-4-OCTANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-methyloctan-4-ol (40575-41-5) → 2-methyloctan-4-one (7492-38-8)

Guidance literature:

With jones' reagent;

DOI:10.1023/B:JOEC.0000006377.13235.4b

Reference yield: 79.0%

oxalyl dichloride (79-37-8) + 2-methyloctan-4-ol (40575-41-5) + dimethyl sulfoxide (67-68-5,8070-53-9) → 2-methyloctan-4-one (7492-38-8)

Guidance literature:

With triethylamine; In water; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield: 56.0%

tributyl borane (122-56-5) + isopentanoyl chloride (108-12-3) → 2-methyloctan-4-one (7492-38-8)

Guidance literature:

With potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 65 ℃; for 3h;

DOI:10.1016/S0040-4039(99)02226-1

upstream raw materials:

2-methyloctan-4-ol

2-methyl-oct-5-en-4-one

di-n-butylcadmium

isopentanoyl chloride

Downstream raw materials:

N-benzyl-2-methyl-4-aminooctane

2-methyloctan-4-ol

Refernces

• 1、 Perez,Campos,Chinchilla,Oehlschlager,Gries,Gries,Giblin-Davis,Castrillo,Pena,Duncan,Gonzalez,Pierce Jr.,McDonald,Andrade. "Aggregation pheromones and host kairomones of West Indian sugarcane weevil, Metamasius hemipterus sericeus". . p. 869 - 888. Retrieved 2007/10/03.
• 2、 Ager, David J.. "The Synthesis of Ketones via α-Silyl Sulphides". . p. 195 - 204. Retrieved 2007/10/02.