10.1021/ic900627g
The research focuses on the synthesis and photophysical characterization of new boron-containing two-photon absorbing fluorophores centered on a pyrazabole core. The study explores the fine-tuning of these fluorophores' one- and two-photon properties by modifying the central core and donor groups. Key chemicals involved in the synthesis include 4-iodopyrazole, tributylborane, 4-bromophenylboronic acid, trimethylsilylacetylene, tetrabutylammonium fluoride, and various donor groups such as alkoxy, diphenylamino, and boron dipyromethene (BODIPY) groups. The synthesized fluorophores exhibit efficient fluorescence and high two-photon absorption cross-sections, making them suitable for two-photon excited microscopy (TPEM) applications. The research also includes molecular calculations to understand the electronic structure and photophysical behavior of these compounds, highlighting their potential for bioimaging and other multiphoton applications.