Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester

Base Information

Chemical Name:Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester
CAS No.:868615-40-1
Molecular Formula:C24H35F3O5S
Molecular Weight:492.6
Hs Code.:

Propanoic acid, 2,2-dimethyl-,
[1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2-
cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester

Synonyms:

Suppliers and Price of Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester

There total 17 articles about Propanoic acid, 2,2-dimethyl-, [1-[2-[(1S)-1-methyl-3-(1-methylethyl)-2-[[(trifluoromethyl)sulfonyl]oxy]-2- cyclopenten-1-yl]ethyl]-2,5-cyclohexadien-1-yl]methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: Trifluoro-methanesulfonic acid (S)-5-[2-(1-hydroxymethyl-4-oxo-cyclohexa-2,5-dienyl)-ethyl]-2-isopropyl-5-methyl-cyclopent-1-enyl ester

: 3282-30-2
pivaloyl chloride

: 868615-40-1
(1S)-{1-[2-(3-isopropyl-1-methyl-2-{[(trifluoromethyl)sulfonyl]oxy}cyclopent-2-en-1-yl)ethyl]cyclohexa-2,5-dien-1-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1016/j.tetlet.2005.07.157

Reference yield: 71.0%

: 868615-51-4
(5S)-5-{2-[1-(hydroxymethyl)cyclohexa-2,5-dien-1-yl]ethyl}-2-isopropyl-5-methylcyclopent-1-en-1-yl trifluoromethanesulfonate

: 3282-30-2
pivaloyl chloride

: 868615-40-1
(1S)-{1-[2-(3-isopropyl-1-methyl-2-{[(trifluoromethyl)sulfonyl]oxy}cyclopent-2-en-1-yl)ethyl]cyclohexa-2,5-dien-1-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1002/ejoc.200600429

Reference yield:

: 868615-30-9
methyl (1R)-1-[2-(3-isopropyl-1-methyl-2-{[(trifluoromethyl)sulfonyl]oxy}cyclopent-2-en-1-yl)ethyl]cyclohexa-2,5-diene-1-carboxylate

: 868615-40-1
(1S)-{1-[2-(3-isopropyl-1-methyl-2-{[(trifluoromethyl)sulfonyl]oxy}cyclopent-2-en-1-yl)ethyl]cyclohexa-2,5-dien-1-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / DIBAL-H / CH₂Cl₂; toluene / 1 h / -78 °C

2: 71 percent / DMAP; triethylamine / CH₂Cl₂ / 4 h / 20 °C

With dmap; diisobutylaluminium hydride; triethylamine; In dichloromethane; toluene;
DOI:10.1002/ejoc.200600429