Sulodexide

Base Information

Chemical Name:Sulodexide
CAS No.:57817-83-1
Molecular Formula:C12H17N5O4
Molecular Weight:295.2945
Hs Code.:
UNII:LEV25J2GTV
DSSTox Substance ID:DTXSID50206530
Nikkaji Number:J3.435.070A
Wikidata:Q76390076
NCI Thesaurus Code:C152467

Synonyms:N(6),O(2)-dimethyladenosine

Suppliers and Price of Sulodexide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Sulodexide

Chemical Property:

Boiling Point:606.5°Cat760mmHg
Flash Point:320.6°C
Density:1.68g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:295.12805404
Heavy Atom Count:21
Complexity:363

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)OC
Isomeric SMILES:CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OC
Recent ClinicalTrials:Sulodexide in the Treatment of Chronic Primary Venous Disease of the Lower Extremities
Recent EU Clinical Trials:Endothelial protection in convalecent COVID-19 patients. The effect of Sulodexide on serum levels of biomarkers for endothelial dysfunction. A prospective, randomized, placebo-controlled, investigator-initiated trial.

Technology Process of Sulodexide

There total 15 articles about Sulodexide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 17287-03-5
trimethylsulphonium hydroxide

: 58-61-7
adenosine

: 60037-52-7
N⁶,O^3'-methyladenosine

: 57817-83-1
N⁶,O^2'-methyladenosine

: 2140-79-6
2'-O-methyl adenosine

: 10300-22-8
3'-O-methyladenosine

Guidance literature:: With copper acetylacetonate; In N,N-dimethyl-formamide; at 70 ℃; for 1h; Further byproducts given;
DOI:10.1021/jo01307a026

Reference yield: 31.0%

: 74230-06-1
trimethylselenonium hydroxyde

: 58-61-7
adenosine

: 60037-52-7
N⁶,O^3'-methyladenosine

: 57817-83-1
N⁶,O^2'-methyladenosine

: 2140-79-6
2'-O-methyl adenosine

: 10300-22-8
3'-O-methyladenosine

Guidance literature:: With copper acetylacetonate; In methanol; N,N-dimethyl-formamide; at 70 ℃; for 0.5h; Further byproducts given;

Reference yield: 28.0%

: 17287-03-5
trimethylsulphonium hydroxide

: 58-61-7
adenosine

: 57817-83-1
N⁶,O^2'-methyladenosine

: 20649-46-1
2'-O,3'-O-dimethyladenosine

: 2140-79-6
2'-O-methyl adenosine

: 10300-22-8
3'-O-methyladenosine

Guidance literature:: With bis(acetylacetonate)nickel(II); In N,N-dimethyl-formamide; at 70 ℃; for 1h; Further byproducts given;
DOI:10.1021/jo01307a026