Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

Base Information

Chemical Name:Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate
CAS No.:65540-54-7
Molecular Formula:C16H18O2
Molecular Weight:242.318
Hs Code.:2916399090
European Community (EC) Number:265-813-7
DSSTox Substance ID:DTXSID60984135
Nikkaji Number:J307.430G

Synonyms:65540-54-7;EINECS 265-813-7;Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate;Ethyl 3,3-dimethylspiro[cyclopropane-1,1'-[1h]indene]-2-carboxylate;SCHEMBL11243033;DTXSID60984135;ILSQQIOQNIKPAG-UHFFFAOYSA-N;ETHYL 3,3-DIMETHYLSPIRO[CYCLOPROPANE-1,1'-INDENE]-2-CARBOXYLATE;3,3-Dimethylspiro[cyclopropane-1,1'-indene]- 2-carboxylic acid, ethyl ester

Suppliers and Price of Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

Chemical Property:

Boiling Point:333.1°Cat760mmHg
Flash Point:148.5°C
PSA：26.30000
Density:1.13g/cm³
LogP:3.17030
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:242.130679813
Heavy Atom Count:18
Complexity:396

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1C(C12C=CC3=CC=CC=C23)(C)C

Technology Process of Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

There total 4 articles about Ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 7380-81-6
ethyl (dimethylsulfuranylidene)acetate

: 34472-48-5
1-(1-methylethylidene)-1H-indene

: 65540-54-7
ethyl 3,3-dimethylspiro-2-carboxylate

Guidance literature:: at 60 - 70 ℃; under 1 Torr;

Reference yield: 39.0%

: 623-73-4
diazoacetic acid ethyl ester

: 34472-48-5
1-(1-methylethylidene)-1H-indene

: 65540-54-7
ethyl 3,3-dimethylspiro-2-carboxylate

: 122603-23-0
ethyl 1-isopropylideneindeno<2,3-b>cyclopropane-1-carboxylate

Guidance literature:: With rhodium(II) acetate; Ambient temperature;

Reference yield:

: 95-13-6
1-indene

: 65540-54-7
ethyl 3,3-dimethylspiro-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / CH₃ONa / 55 - 70 °C

2: 11 percent / rhodium acetate / Ambient temperature

With rhodium(II) acetate; sodium methylate;