4-(2-Bromoethoxy)-3-fluorobenzonitrile

Base Information

Chemical Name:4-(2-Bromoethoxy)-3-fluorobenzonitrile
CAS No.:872045-88-0
Molecular Formula:C9H7BrFNO
Molecular Weight:244.063
Hs Code.:
DSSTox Substance ID:DTXSID70580541
Wikidata:Q82471391

Synonyms:4-(2-Bromoethoxy)-3-fluorobenzonitrile;872045-88-0;4-(2-Bromo-ethoxy)-3-fluorobenzonitrile;SCHEMBL3119850;DTXSID70580541;AJWRIWXNSIYISH-UHFFFAOYSA-N

Suppliers and Price of 4-(2-Bromoethoxy)-3-fluorobenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(2-Bromoethoxy)-3-fluorobenzonitrile

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:242.96950
Heavy Atom Count:13
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C#N)F)OCCBr

Technology Process of 4-(2-Bromoethoxy)-3-fluorobenzonitrile

There total 3 articles about 4-(2-Bromoethoxy)-3-fluorobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 405-04-9
3-fluoro-4-hydroxybenzonitrile

: 106-93-4
ethylene dibromide

: 872045-88-0
4-(2-bromoethoxy)-3-fluorobenzonitrile

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; Inert atmosphere;

Reference yield:

: 331-62-4
3-fluoro-4-methoxybenzonitrile

: 872045-88-0
4-(2-bromoethoxy)-3-fluorobenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 72 h / 0 °C / Inert atmosphere; Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 60 °C / Inert atmosphere

With boron tribromide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 2357-52-0
3-fluoro-4-methoxyphenyl bromide

: 872045-88-0
4-(2-bromoethoxy)-3-fluorobenzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 120 °C

2: boron tribromide / dichloromethane / 72 h / 0 °C / Inert atmosphere; Reflux

3: potassium carbonate / N,N-dimethyl-formamide / 60 °C / Inert atmosphere

With boron tribromide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;