Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate

Base Information

Chemical Name:Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate
CAS No.:872604-78-9
Molecular Formula:C18H18N2O3
Molecular Weight:310.34700
Hs Code.:
DSSTox Substance ID:DTXSID00588656
Wikidata:Q82481470
Mol file:872604-78-9.mol

Synonyms:872604-78-9;Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate;[2-(4-Methoxy-phenyl)-benzoimidazol-1-yl]-acetic acid ethyl ester;DTXSID00588656;AKOS003164655;DB-362532

Suppliers and Price of Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[2-(4-METHOXY-PHENYL)BENZOIMIDAZOL-1-YL]ACETIC ACID ETHYL ESTER 95.00%
5MG
$ 495.24

Total 2 raw suppliers

Chemical Property of Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate

Chemical Property:

Vapor Pressure:1.63E-09mmHg at 25°C
Boiling Point:483.8oC at 760 mmHg
Flash Point:246.4oC
PSA：53.35000
Density:1.18g/cm3
LogP:3.27500
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:310.13174244
Heavy Atom Count:23
Complexity:396

Purity/Quality:

98% ^*data from raw suppliers

[2-(4-METHOXY-PHENYL)BENZOIMIDAZOL-1-YL]ACETIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1C2=CC=CC=C2N=C1C3=CC=C(C=C3)OC

Technology Process of Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate

There total 3 articles about Ethyl [2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 2620-81-7
2-(4-methoxyphenyl)-1H-benzimidazole

: 105-39-5
chloroacetic acid ethyl ester

: 872604-78-9
[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]-acetic acid ethyl ester

Guidance literature:: With potassium hydroxide; In dimethyl sulfoxide; for 2h;
DOI:10.1016/j.bmc.2008.02.077

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 872604-78-9
[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium metabisulfite

2: potassium hydroxide / dimethyl sulfoxide

With sodium metabisulfite; potassium hydroxide; In dimethyl sulfoxide;
DOI:10.1016/j.ejmech.2019.04.012

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 872604-78-9
[2-(4-methoxyphenyl)-1H-benzimidazol-1-yl]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium metabisulfite

2: potassium hydroxide / dimethyl sulfoxide

With sodium metabisulfite; potassium hydroxide; In dimethyl sulfoxide;
DOI:10.1016/j.ejmech.2019.04.012