N-Benzyl-2-chlorobenzaMide, 97%

Base Information

• Chemical Name: N-Benzyl-2-chlorobenzaMide, 97%
• CAS No.: 7506-50-5
• Molecular Formula: C14H12ClNO
• Molecular Weight: 245.708
• Mol file: 7506-50-5.mol

Synonyms:2-Chlor-N-benzyl-benzamid;N-Benzyl-2-chloro-benzamide;2-chloro-N-benzylbenzamide;2-chloro-benzoic acid benzylamide;2-Chlor-benzoesaeure-benzylamid;N1-benzyl-2-chlorobenzamide;

Chemical Property of N-Benzyl-2-chlorobenzaMide, 97%

Chemical Property:

• Vapor Pressure: 2.82E-07mmHg at 25°C
• Boiling Point: 420.4°Cat760mmHg
• Flash Point: 208.1°C
• PSA: 29.10000
• Density: 1.213g/cm³
• LogP: 3.66090

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Benzyl-2-chlorobenzaMide, 97%

There total 12 articles about N-Benzyl-2-chlorobenzaMide, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

o-chlorobenzoyl chloride (609-65-4) + benzylamine (100-46-9) → N-(o-chlorobenzoyl)benzylamine (7506-50-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/jo802604g

Reference yield: 90.0%

benzaldehyde (100-52-7) + 2-chlorobenzamide (609-66-5) → N-(o-chlorobenzoyl)benzylamine (7506-50-5)

Guidance literature:

With L-Tartaric acid; hydrogen; In toluene; at 135 ℃; for 24h; under 37503.8 Torr; Reagent/catalyst; Autoclave;

DOI:10.1016/j.tet.2021.132526

Reference yield: 85.0%

benzylamine (100-46-9) + ortho-chlorobenzoic acid (118-91-2) → N-(o-chlorobenzoyl)benzylamine (7506-50-5)

Guidance literature:

ortho-chlorobenzoic acid; With N-chlorobenzotriazole; triphenylphosphine; In dichloromethane; for 0.25h;

benzylamine; With triethylamine; In dichloromethane; at 20 ℃; for 0.583333h;

DOI:10.1080/10426507.2015.1024313

upstream raw materials:

benzylamine

ortho-chlorobenzoic acid

o-chlorobenzoyl chloride

2-Chlorobenzonitrile

Downstream raw materials:

N-benzyl-o-chlorothiobenzamide

benzaldehyde

2-chlorobenzamide

3-Benzenesulfonyl-2-benzyl-2,3-dihydro-isoindol-1-one