diethyl (2,2-dimethylpropylidene)propanedioate

Base Information

• Chemical Name: diethyl (2,2-dimethylpropylidene)propanedioate
• CAS No.: 17085-89-1
• Molecular Formula: C12H20 O4
• Molecular Weight: 228.288
• Mol file: 17085-89-1.mol

Synonyms:Malonicacid, neopentylidene-, diethyl ester (6CI,8CI); Propanedioic acid,(2,2-dimethylpropylidene)-, diethyl ester (9CI); NSC 71599

Chemical Property of diethyl (2,2-dimethylpropylidene)propanedioate

Chemical Property:

• Vapor Pressure: 0.0239mmHg at 25°C
• Boiling Point: 248.7°Cat760mmHg
• Flash Point: 108.1°C
• Density: 1.005g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl (2,2-dimethylpropylidene)propanedioate

There total 3 articles about diethyl (2,2-dimethylpropylidene)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

pivalaldehyde (630-19-3) + diethyl malonate (105-53-3) → diethyl 2-(2,2-dimethylpropylidene)malonate (17085-89-1)

Guidance literature:

With acetic anhydride; zinc(II) chloride; for 72h; Reflux; Inert atmosphere;

DOI:10.1002/ejoc.202100430

Reference yield: 18.6%

pivalaldehyde (630-19-3) + diethyl malonate (105-53-3) → diethyl 2-(2,2-dimethylpropylidene)malonate (17085-89-1) + ethyl (E)-4,4-dimethyl-2-pentenoate (22147-62-2)

Guidance literature:

With pyrrolidine anchored in non-ordered mesoporous silica hybrid materials; at 200 ℃; for 8h; Microwave irradiation; Sealed tube;

DOI:10.1002/cctc.202101031

Reference yield:

→ diethyl 2-(2,2-dimethylpropylidene)malonate (17085-89-1)

Guidance literature:

Malonsaeurediaethylester, Pivalaldehyd;

upstream raw materials:

pivalaldehyde

diethyl malonate

Downstream raw materials:

5-allyl-5-(2,2-dimethyl-propyl)-pyrimidine-2,4,6-trione

diethyl (2,2-dimethylpropyl)malonate

β-tert-butylacrylic acid