1-AMINO-3-BENZYLOXY-PROPAN-2-OL

Base Information

• Chemical Name: 1-AMINO-3-BENZYLOXY-PROPAN-2-OL
• CAS No.: 90503-15-4
• Molecular Formula: C10H15NO2
• Molecular Weight: 181.23
• Hs Code.: 2922509090
• Mol file: 90503-15-4.mol

Synonyms:1-AMINO-3-BENZYLOXY-PROPAN-2-OL;TIMTEC-BB SBB010672;3-BENZYLOXY-2-HYDROXY-1-PROPYLAMINE

Chemical Property of 1-AMINO-3-BENZYLOXY-PROPAN-2-OL

Chemical Property:

• Vapor Pressure: 6.01E-05mmHg at 25°C
• Boiling Point: 331.9°Cat760mmHg
• Flash Point: 154.5°C
• PSA: 55.48000
• Density: 1.11g/cm³
• LogP: 1.22310

Purity/Quality:

99% ^*data from raw suppliers

1-Amino-3-benzyloxy-propan-2-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Amino-3-benzyloxy-propan-2-ol can be used for its aldose reductase-inhibiting activity to treat diseases caused by insulin resistance.

Technology Process of 1-AMINO-3-BENZYLOXY-PROPAN-2-OL

There total 8 articles about 1-AMINO-3-BENZYLOXY-PROPAN-2-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Benzyloxymethyl-oxiran (2930-05-4) → (RS)-(3-benzyloxy-2-hydroxypropyl)amine (90503-15-4)

Guidance literature:

With ammonium hydroxide; 1.) 5 deg C, 8 h, 2.) R_.T_., 16 h.;

Reference yield: 72.0%

(R,S)-1-azido-3-benzyloxy-2-propanol (99805-19-3) → (RS)-(3-benzyloxy-2-hydroxypropyl)amine (90503-15-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 1h; under 760 Torr;

DOI:10.1248/cpb.40.609

Reference yield:

(R,S)-1-azido-3-benzyloxy-2-propanol (99805-19-3) → 3-(3-chlorophenoxy)-2-hydroxypropylamine (4698-86-6) + (RS)-(3-benzyloxy-2-hydroxypropyl)amine (90503-15-4)

Guidance literature:

In tetrahydrofuran;

upstream raw materials:

Benzyloxymethyl-oxiran

2-(3-(benzyloxy)-2-hydroxypropyl)isoindoline-1,3-dione

(R,S)-1-azido-3-benzyloxy-2-propanol

3-benzyloxypropan-1,2-diol

Downstream raw materials:

2-{ [3-(benzyloxy)-2-hydroxypropyl]amino}-4-phenylbutan-1-ol

1-benzyloxy-2-chloromethoxy-3-phthaloylimidopropane

trans-5-benzyloxymethyl-3-formyl-2-methyl-1,3-oxazolidine

cis-5-benzyloxymethyl-3-formyl-2-methyl-1,3-oxazolidine

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