2-Phenyl-1,4-dihydroquinoline

Base Information

• Chemical Name: 2-Phenyl-1,4-dihydroquinoline
• CAS No.: 88062-14-0
• Molecular Formula: C15H13N
• Molecular Weight: 207.275
• DSSTox Substance ID: DTXSID20516370
• Wikidata: Q82377763
• Mol file: 88062-14-0.mol

Synonyms:2-Phenyl-1,4-dihydroquinoline;88062-14-0;DTXSID20516370

Chemical Property of 2-Phenyl-1,4-dihydroquinoline

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 207.104799419
• Heavy Atom Count: 16
• Complexity: 263

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C=C(NC2=CC=CC=C21)C3=CC=CC=C3

Technology Process of 2-Phenyl-1,4-dihydroquinoline

There total 10 articles about 2-Phenyl-1,4-dihydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-hydroxy 1-phenyl indane (36374-47-7) → 1,4-dihydro 2-phenyl quinoline (88062-14-0)

Guidance literature:

With tris-(2-chloro-ethyl)-amine; sulfuric acid;

DOI:10.1016/S0040-4039(00)88181-2

Reference yield:

2-(3-phenylprop-2-ynyl)aniline (1159987-17-3) → 2-Phenylquinoline (612-96-4) + 2-(3-phenylpropyl)aniline (76691-97-9) + 1,4-dihydro 2-phenyl quinoline (88062-14-0) + (S)-2-phenyl-1,2,3,4-tetrahydroquinoline

Guidance literature:

With (1,3-dimesitylimidazol-2-ylidene)gold(I) chloride; hydrogen; In isopropyl alcohol; at 25 ℃; for 24h; under 38002.6 Torr;

DOI:10.1021/acs.organomet.9b00183

Reference yield:

2-(3-phenylprop-2-ynyl)aniline (1159987-17-3) → 2-Phenylquinoline (612-96-4) + 2-(3-phenylprop-2-enyl)aniline (108716-00-3) + 2-(3-phenylpropyl)aniline (76691-97-9) + 1,4-dihydro 2-phenyl quinoline (88062-14-0) + (S)-2-phenyl-1,2,3,4-tetrahydroquinoline

Guidance literature:

With [IMesAuMe]; C₃₂H₃₅F₃N₂O₅RuS₂; hydrogen; In methanol; at 25 ℃; for 24h; under 38002.6 Torr; Reagent/catalyst; Solvent;

DOI:10.1021/acs.organomet.9b00183

upstream raw materials:

1-hydroxy 1-phenyl indane

inden-1-one

C₂₀H₂₁NO₂

2-(3-phenylprop-2-ynyl)aniline

Downstream raw materials:

2-Phenylquinoline