1159987-17-3

Upstream product

• 166329-43-7 N-tert-butoxycarbonyl-2-bromomethylaniline 
• 1159987-75-3 C₁₅H₁₁NO₂ 
• 1159987-56-0 C₂₀H₂₁NO₂ 

Downstream Products

• 108716-00-3 2-(3-phenylprop-2-enyl)aniline 
• 76691-97-9 2-(3-phenylpropyl)aniline 
• 612-96-4 2-Phenylquinoline 
• 88062-14-0 1,4-dihydro 2-phenyl quinoline 
• 24005-23-0 2-phenyl-1,2,3,4-tetrahydroquinoline 
• 1227292-28-5 C₃₂H₂₇BrN₂O₂ 

Relevant academic research and scientific papers

A Synthetic Route to Chiral Benzo-Fused N-Heterocycles via Sequential Intramolecular Hydroamination and Asymmetric Hydrogenation of Anilino-Alkynes

An efficient sequential intramolecular hydroamination/asymmetric hydrogenation reaction under catalysis of a single chiral ruthenium complex or a binary system consisting of achiral gold complex and chiral ruthenium complex has been reported. A diverse range of enantioenriched benzo-fused N-heterocycles, including 1,2,3,4-tetrahydroquinoline, indoline, and 2,3,4,5-tetrahydro-1H-benzo[b]azepine derivatives, were obtained from anilino-alkynes in high yields (up to 98%) with moderate to excellent enantioselectivities (up to 98% ee) under mild conditions. This protocol features good functional group tolerance and high atom economy. Furthermore, this catalytic protocol is applicable to gram-scale synthesis of a naturally occurring alkaloid, (-)-Angustureine.

Consecutive intramolecular hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Bronsted acid binary system

(Chemical Equation Presented) Consecutive hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Bronsted acid binary system has been described for the direct transformation of 2-(2-propynyl)aniline deriva