12-Benzyloxy-2,2-dimethyldodecanoic acid

Base Information

Chemical Name:12-Benzyloxy-2,2-dimethyldodecanoic acid
CAS No.:88088-74-8
Molecular Formula:C21H34O3
Molecular Weight:334.499
Hs Code.:
DSSTox Substance ID:DTXSID30541799
Wikidata:Q82418242

Synonyms:12-benzyloxy-2,2-dimethyldodecanoic acid;88088-74-8;SCHEMBL10781848;DTXSID30541799;ROHGNMQWLGYWIG-UHFFFAOYSA-N;12-(BENZYLOXY)-2,2-DIMETHYLDODECANOIC ACID

Suppliers and Price of 12-Benzyloxy-2,2-dimethyldodecanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 12-Benzyloxy-2,2-dimethyldodecanoic acid

Chemical Property:

XLogP3:6.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:14
Exact Mass:334.25079494
Heavy Atom Count:24
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CCCCCCCCCCOCC1=CC=CC=C1)C(=O)O

Technology Process of 12-Benzyloxy-2,2-dimethyldodecanoic acid

There total 3 articles about 12-Benzyloxy-2,2-dimethyldodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 16423-62-4
dilithiated 2-methylpropionic acid

: 88088-72-6
(((10-bromodecyl)oxy)methyl)benzene

: 88088-74-8
12-benzyloxy-2,2-dimethyldodecanoic acid

Guidance literature:: In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; 1.) -60 deg C; 2.) r.t.;
DOI:10.1246/cl.1983.1387

Reference yield:

: 4101-68-2
1,10-dibromodecane

: 88088-74-8
12-benzyloxy-2,2-dimethyldodecanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / tetrahydrofuran; phenylmethanol / 5 h / Heating

2: 1.) lithium diisopropylamide, hexamethylphosphoric triamide / 1.) THF, hexane, 50 deg C, 1 h, 2.) THF, hexane, 45 deg C, 2 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; benzyl alcohol;

Reference yield:

: 20194-18-7
sodium phenyl-methanolate

: 88088-74-8
12-benzyloxy-2,2-dimethyldodecanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / tetrahydrofuran; phenylmethanol / 5 h / Heating

2: 1.) lithium diisopropylamide, hexamethylphosphoric triamide / 1.) THF, hexane, 50 deg C, 1 h, 2.) THF, hexane, 45 deg C, 2 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; benzyl alcohol;