Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate

Base Information

Chemical Name:Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate
CAS No.:88113-21-7
Molecular Formula:C18H15ClO4
Molecular Weight:330.768
Hs Code.:
DSSTox Substance ID:DTXSID50708322

Synonyms:88113-21-7;Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate;DTXSID50708322;KPYMPIYCXQNHOF-UHFFFAOYSA-N;ethyl 3-[4-(3-chlorophenoxy)benzoyl]acrylate

Suppliers and Price of Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:330.0658866
Heavy Atom Count:23
Complexity:427

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=CC(=O)C1=CC=C(C=C1)OC2=CC(=CC=C2)Cl

Technology Process of Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate

There total 3 articles about Ethyl 4-[4-(3-chlorophenoxy)phenyl]-4-oxobut-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.7%

: 64-67-5
diethyl sulfate

: 88112-89-4
3-<4-(3-chlorophenoxy)benzoyl>acrylic acid

: 88113-21-7
ethyl 3-<4-(3-chlorophenoxy)benzoyl>acrylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1248/cpb.34.701

Reference yield:

: 88112-89-4
3-<4-(3-chlorophenoxy)benzoyl>acrylic acid

: 88113-21-7
ethyl 3-<4-(3-chlorophenoxy)benzoyl>acrylate

Guidance literature:

Reference yield:

: 6452-49-9
1-chloro-3-phenoxybenzene

: 88113-21-7
ethyl 3-<4-(3-chlorophenoxy)benzoyl>acrylate

Guidance literature:: Multi-step reaction with 2 steps

1: 58.5 percent / AlCl₃ / CH₂Cl₂ / 4 h / Ambient temperature

2: 86.7 percent / K₂CO₃ / dimethylformamide / 3 h / Ambient temperature

With aluminium trichloride; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.701