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1-chloro-3-phenoxybenzene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

6452-49-9

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6452-49-9 Usage

Classification

Chlorinated aromatic hydrocarbon

Usage

Intermediate in the production of pesticides and other organic chemicals

Physical State at Room Temperature

White crystalline solid

Molecular Weight

204.66 g/mol

Safety Precautions

Can be harmful if ingested or inhaled

Potential Hazards

Causes irritation to the skin and eyes

Handling Recommendations

Use proper protective equipment and follow safety protocols

Check Digit Verification of cas no

The CAS Registry Mumber 6452-49-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,5 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6452-49:
(6*6)+(5*4)+(4*5)+(3*2)+(2*4)+(1*9)=99
99 % 10 = 9
So 6452-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H9ClO/c13-10-5-4-8-12(9-10)14-11-6-2-1-3-7-11/h1-9H

6452-49-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Chloro-3-phenoxybenzene

1.2 Other means of identification

Product number -
Other names Ether,m-chlorophenyl phenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6452-49-9 SDS

6452-49-9Relevant academic research and scientific papers

CoII Immobilized on Aminated Magnetic-Based Metal–Organic Framework: An Efficient Heterogeneous Nanostructured Catalyst for the C–O Cross-Coupling Reaction in Solvent-Free Conditions

Mohammadinezhad, Arezou,Akhlaghinia, Batool

, p. 332 - 352 (2020/01/11)

Abstract: In this paper, we report the synthesis of Fe3O4?AMCA-MIL53(Al)-NH2-CoII NPs based on the metal–organic framework structures as a magnetically separable and environmentally friendly heterogeneous nanocatalyst. The prepared nanostructured catalyst efficiently promotes the C–O cross-coupling reaction in solvent-free conditions without the need for using toxic solvents and/or expensive palladium catalyst. Graphic Abstract: [Figure not available: see fulltext.].

Trimethoxyphenyl (TMP) as a Useful Auxiliary for in situ Formation and Reaction of Aryl(TMP)iodonium Salts: Synthesis of Diaryl Ethers

Gallagher, Rory T.,Basu, Souradeep,Stuart, David R.

, p. 320 - 325 (2019/12/11)

Herein, we describe a synthetic approach for arylation that exploits the in situ formation and reaction of an unsymmetrical diaryliodonium salt. In this way, aryl iodides are used as reagents in a metal-free reaction with phenols, and a trimethoxyphenyl (TMP) group is used as a “dummy” group to facilitate transfer of a wide range of aryl moieties. The scope of aryl electrophiles and phenol nucleophiles is broad (>30 examples) and the yields are high (52–95%, 80% avg.). One-pot coupling reactions avoid the synthesis of diaryliodonium salts and provide opportunities for sequential reactions and novel chemoselectivity. (Figure presented.).

Copper-mediated synthesis of mono- and dichlorinated diaryl ethers

?ermák, Jan K.,Církva, Vladimír

supporting information, p. 4185 - 4188 (2014/07/22)

An efficient synthesis of polychlorinated diphenyl ethers (PCDEs) using the Cu(OAc)2-catalyzed Chan-Lam coupling reaction is described. A library of all possible mono- and dichlorinated diphenyl ether congeners was prepared and characterized using MS, 1H, and 13C NMR spectroscopy, and Kovats retention indices. Our approach, using the optimized reaction conditions (i.e., reaction temperature, oxidizing atmosphere and base), significantly improves and simplifies the process compared to previously reported syntheses.

Iron-catalyzed C-O cross-couplings of phenols with aryl iodides

Bistri, Olivia,Correa, Arkaitz,Bolm, Carsten

, p. 586 - 588 (2008/09/20)

(Chemical Equation Presented) Low-price coupling: A versatile, practical, and cost-efficient iron-catalyzed O-arylation protocol is applied to the synthesis of a variety of diaryl ethers, which are formed in high yields. Best results were obtained by using FeCl3 and a β-diketo ligand.

Reactions of diphenyl ether with chlorine and bromine atoms around 750 K - Relevance for gas-phase 'dioxin' formation

Wiater, Izabela,Louw, Robert

, p. 261 - 265 (2007/10/03)

The title reactions have been studied to scrutinize rate data recently inferred for the two reverse steps - reaction of phenoxy radicals with chlorobenzene and bromobenzene which were at variance with commonly accepted model values. Both with chlorine and bromine atoms, splitting to halobenzene and phenoxy radical was found to occur in competition with abstraction of o-, m-, p-hydrogen atoms. On this basis, the displacements of Cl and Br from the benzene ring by phenoxy radicals must have activation energies above 20 kcal/mol, and are therefore slow. As a consequence, formation of 'dioxins' from halogenated phenols, in (slow) combustion, should proceed by combination of two (halo)phenoxy radicals rather than by displacement of (ortho-)halogen in a halophenol molecule.

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