N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine

Base Information

• Chemical Name: N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine
• CAS No.: 88127-64-4
• Molecular Formula: C₁₀H₁₆BrNSi
• Molecular Weight: 258.233
• DSSTox Substance ID: DTXSID40520055
• Wikidata: Q82383666
• Mol file: 88127-64-4.mol

Synonyms:88127-64-4;N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine;DTXSID40520055

Chemical Property of N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 257.02354
• Heavy Atom Count: 13
• Complexity: 167

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C1=CC=CC=C1Br)[Si](C)(C)C

Technology Process of N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine

There total 3 articles about N-(2-Bromophenyl)-N,1,1,1-tetramethylsilanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-bromophenyl)formamide (10113-38-9) → (2-Bromo-phenyl)-methyl-trimethylsilanyl-amine (88127-64-4)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / dimethylsulfoxide / 4 h / Ambient temperature

2: 77 percent / H₂SO₄ / H₂O / 2 h / Heating

3: 1.) n-BuLi / 1.) ether/hexane; 2.) ether, 20 deg C, 15 h

With potassium hydroxide; n-butyllithium; sulfuric acid; In water; dimethyl sulfoxide;

Reference yield:

2-bromo-N-methylformanilide (344746-77-6) → (2-Bromo-phenyl)-methyl-trimethylsilanyl-amine (88127-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / H₂SO₄ / H₂O / 2 h / Heating

2: 1.) n-BuLi / 1.) ether/hexane; 2.) ether, 20 deg C, 15 h

With n-butyllithium; sulfuric acid; In water;

Reference yield:

chloro-trimethyl-silane (75-77-4) + 2-bromo-N-methylaniline (6832-87-7) → (2-Bromo-phenyl)-methyl-trimethylsilanyl-amine (88127-64-4)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) ether/hexane; 2.) ether, 20 deg C, 15 h;

upstream raw materials:

chloro-trimethyl-silane

2-bromo-N-methylaniline

N-(2-bromophenyl)formamide

2-bromo-N-methylformanilide