4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate

Base Information

Chemical Name:4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate
CAS No.:88195-82-8
Molecular Formula:C₂₄H₃₇NO₆
Molecular Weight:435.561
Hs Code.:
DSSTox Substance ID:DTXSID20575700
Wikidata:Q82465118

Synonyms:88195-82-8;4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate;DTXSID20575700

Suppliers and Price of 4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate

Chemical Property:

PSA：98.42000
LogP:7.04630
XLogP3:8.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:18
Exact Mass:435.26208790
Heavy Atom Count:31
Complexity:511

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCC(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])OC(=O)C
Isomeric SMILES:CCCCCCCCCCCCCC[C@H](C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])OC(=O)C

Technology Process of 4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate

There total 6 articles about 4-Nitrophenyl (2R)-2-(acetyloxy)hexadecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.8%

: 95603-89-7
D(R)-α-acetoxypalmitic acid

: 658-78-6
1-nitro-4-trifluoroacetoxy-benzene

: 88195-82-8
p-nitrophenyl 2-O-acetyl-(2R)-2-hydroxypalmitate

Guidance literature:: In pyridine; for 18h; Ambient temperature;
DOI:10.1016/S0040-4020(01)96633-5

Reference yield:

: 16742-51-1,78330-57-1,89301-98-4,36451-47-5
methyl (R)-2-hydroxyhexadecanoate

: 88195-82-8
p-nitrophenyl 2-O-acetyl-(2R)-2-hydroxypalmitate

Guidance literature:: Multi-step reaction with 3 steps

1: 87.1 percent / KOH, 2 N HCl / aq. ethanol / 0.33 h / 70 °C

2: 92.4 percent / pyridine / 18 h / Ambient temperature

3: 96.8 percent / pyridine / 18 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; In pyridine; ethanol;
DOI:10.1016/S0040-4020(01)96633-5

Reference yield:

: 112-39-0
hexadecanoic acid methyl ester

: 88195-82-8
p-nitrophenyl 2-O-acetyl-(2R)-2-hydroxypalmitate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) lithium diisopropylamide, 2.) MoO₅*pyridine*HMPA / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, 1 h

2: 42 percent / pyridine / 0.67 h / Ambient temperature

3: KOH / methanol / 1 h / Ambient temperature

4: pyridine / 9 h / Ambient temperature

5: pyridine / 1 h / Ambient temperature

With pyridine; potassium hydroxide; oxodiperoxymolybdenumpyridine hexamethylphosphoric triamide complex; lithium diisopropyl amide; In methanol;
DOI:10.1248/cpb.41.1534