Chemical Property of Methyl palmitate
Chemical Property:
- Appearance/Colour:Clear colorless liquid or low melting solid
- Vapor Pressure:0.000149mmHg at 25°C
- Melting Point:32-35 °C(lit.)
- Refractive Index:n20/D 1.4512(lit.)
- Boiling Point:332.1 °C at 760 mmHg
- Flash Point:152.8 °C
- PSA：26.30000
- Density:0.865 g/cm3
- LogP:5.64070
- Storage Temp.:2-8°C
- Solubility.:Chloroform (Sparingly), Methanol (Slightly)
- Water Solubility.:INSOLUBLE
- XLogP3:7.9
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:15
- Exact Mass:270.255880323
- Heavy Atom Count:19
- Complexity:190
- Purity/Quality:
-
99% *data from raw suppliers
Methyl Palmitate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Biological Agents -> Plant Oils and Extracts
- Canonical SMILES:CCCCCCCCCCCCCCCC(=O)OC
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Description
Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake, and approximately 25% of the total plasma fatty acids in plasma lipoproteins. Saturated free fatty acids induce the expression of cyclooxygenase-2. Palmitic acid methyl ester (MP) is a fatty acid ester whose concentration in cells is modulated by methanol. In studies with isolated Kupffer cells, MP inhibits phagocytosis and decreases cell viability. In cells treated with lipopolysaccharide, it also decreases secretion of interleukin-10, TNF-α, nitric oxide, and prostaglandin E2. This effect is thought to occur by the inhibition of NF-κB.
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Uses
Methyl Palmitate is a fatty acid ester essential oil that naturally occurs in many plant species. Methyl Palmitate concentration in cells are known to be modulated by methanol. In experimental studies
with isolated Kupffer cells, Methyl palmitate exhibited inhibitory activity towards phagocytosis and decreases cell viability. Methyl palmitate can be used as an additive in food and cosmetic industries for the stabilization of fats and oil products by slowing down the auto-oxidation of unsaturated fatty acids. Methyl palmitate is used in the preparation of detergents, emulsifiers, wetting agents, stabilizers, resins, lubricants, plasticizers and animal feeds. It exhibits an anti-inflammatory and anti-fibrotic agent and prevents bleomycin-induced lung inflammation and fibrosis in rats. In addition, it also prevents carbon tetrachloride-induced liver fibrosis linked to reduce transforming growth factor beta, which is a secreted protein that controls proliferation, cellular differentiation and other functions in most cells.
