2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine

Base Information

Chemical Name:2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine
CAS No.:88369-29-3
Molecular Formula:C₁₂H₇ClN₂S
Molecular Weight:246.72
Hs Code.:
DSSTox Substance ID:DTXSID70521550
Wikidata:Q82386086

Synonyms:88369-29-3;2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine;DTXSID70521550

Suppliers and Price of 2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:246.0018471
Heavy Atom Count:16
Complexity:251

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=NC3=C(S2)N=CC=C3)Cl

Technology Process of 2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine

There total 4 articles about 2-(2-Chlorophenyl)[1,3]thiazolo[5,4-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52334-72-2
3-(2'-chlorobenzoyl)aminopyrid-2-one

: 88369-29-3
2-(2'-chlorophenyl)thiazolo<5,4-b>pyridine

Guidance literature:: With tetraphosphorus decasulfide; In pyridine; for 4h; Heating;
DOI:10.1002/jhet.5570200535

Reference yield:

: 6298-19-7
2-chloro-3-aminopyridine

: 88369-29-3
2-(2'-chlorophenyl)thiazolo<5,4-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / toluene / 1 h / Heating

2: 89 percent / NH₄Cl, polyphosphoric acid / 12 h / 180 °C

3: P₂S₅ / pyridine / 4 h / Heating

With pyridine; PPA; tetraphosphorus decasulfide; ammonium chloride; In pyridine; toluene;
DOI:10.1002/jhet.5570200535

Reference yield:

: 84446-21-9
3-(2'-chlorobenzoyl)amino-2-chloropyridine

: 88369-29-3
2-(2'-chlorophenyl)thiazolo<5,4-b>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / NH₄Cl, polyphosphoric acid / 12 h / 180 °C

2: P₂S₅ / pyridine / 4 h / Heating

With PPA; tetraphosphorus decasulfide; ammonium chloride; In pyridine;
DOI:10.1002/jhet.5570200535