ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate

Base Information

Chemical Name:ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate
CAS No.:88585-10-8
Molecular Formula:C12H12N2O3
Molecular Weight:232.239
Hs Code.:
DSSTox Substance ID:DTXSID80586256
Wikidata:Q82478350

Synonyms:88585-10-8;ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate;SCHEMBL4289304;DTXSID80586256;WLKZERYRSTXKEN-UHFFFAOYSA-N;AKOS000277787;DB-416205;ethyl 3-hydroxy-1-phenyl-1H-pyrazole-4-carboxylate;Ethyl 2,3-dihydro-3-oxo-1-phenyl-1H-pyrazole-4-carboxylate;3-Oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid ethyl ester

Suppliers and Price of ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:346

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN(NC1=O)C2=CC=CC=C2

Technology Process of ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate

There total 3 articles about ethyl 3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 114-83-0
1-acetyl-2-phenylhydrazine

: 88585-10-8
4-ethoxycarbonyl-2-phenyl-3-pyrazolin-5-one

Guidance literature:: With trichlorophosphate; at 70 ℃; for 3h;
DOI:10.1016/S0040-4020(01)89994-4

Reference yield: 18.0%

: 100-63-0
phenylhydrazine

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 88585-10-8
4-ethoxycarbonyl-2-phenyl-3-pyrazolin-5-one

: 111491-32-8
2-<2,2-bis(ethoxycarbonyl)ethenyl>-1-phenylhydrazine

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; for 4.5h; Ambient temperature;
DOI:10.1016/S0040-4020(01)89994-4