Bis[(4-chlorophenyl)methyl](methyl)amine

Base Information

• Chemical Name: Bis[(4-chlorophenyl)methyl](methyl)amine
• CAS No.: 6970-85-0
• Molecular Formula: C15H15 Cl2 N
• Molecular Weight: 280.197
• NSC Number: 62608
• DSSTox Substance ID: DTXSID20289653
• Nikkaji Number: J390.527F
• Wikidata: Q82027058
• Mol file: 6970-85-0.mol

Synonyms:6970-85-0;n-(4-chlorobenzyl)-1-(4-chlorophenyl)-n-methylmethanamine;BIS[(4-CHLOROPHENYL)METHYL](METHYL)AMINE;NSC62608;NCIOpen2_002572;SCHEMBL18532755;DTXSID20289653;1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-N-methylmethanamine;NSC 62608;NSC-62608;4-Chloro-N-methyl-N-(4-chlorobenzyl)benzenemethanamine

Chemical Property of Bis[(4-chlorophenyl)methyl](methyl)amine

Chemical Property:

• Vapor Pressure: 6.26E-05mmHg at 25°C
• Boiling Point: 345.2°Cat760mmHg
• Flash Point: 162.6°C
• Density: 1.214g/cm³
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 279.0581549
• Heavy Atom Count: 18
• Complexity: 207

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(CC1=CC=C(C=C1)Cl)CC2=CC=C(C=C2)Cl

Technology Process of Bis[(4-chlorophenyl)methyl](methyl)amine

There total 3 articles about Bis[(4-chlorophenyl)methyl](methyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

glycine (56-40-6,18875-39-3,25718-94-9) + para-Chlorobenzyl alcohol (873-76-7) → bis-(4-chloro-benzyl)-methyl-amine (6970-85-0)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium hydroxide; In toluene; at 110 ℃; Inert atmosphere;

DOI:10.1055/s-0033-1340474

Reference yield:

4-chlorobenzyl bromide (622-95-7) + methylamine (74-89-5) → bis-(4-chloro-benzyl)-methyl-amine (6970-85-0) + N-methyl-4-chlorobenzylamine (104-11-0)

Guidance literature:

With ethanol; water; at 30 - 40 ℃;

Reference yield:

1-Chloro-4-(chloromethyl)benzene (104-83-6) + methylamine (74-89-5) → bis-(4-chloro-benzyl)-methyl-amine (6970-85-0)

Guidance literature:

DOI:10.1021/ja01523a059

upstream raw materials:

1-Chloro-4-(chloromethyl)benzene

methylamine

4-chlorobenzyl bromide

glycine