Methyl 2-benzamidopropanoate

Base Information

Chemical Name:Methyl 2-benzamidopropanoate
CAS No.:7260-27-7
Molecular Formula:C11H13NO3
Molecular Weight:207.229
Hs Code.:
NSC Number:173195
DSSTox Substance ID:DTXSID00274749,DTXSID30993254
Nikkaji Number:J1.400.828D

Synonyms:N-benzoylalanine methyl ester;N-benzoylalanine methyl ester, (D)-isomer

Suppliers and Price of Methyl 2-benzamidopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Methyl 2-benzamidopropanoate

Chemical Property:

Boiling Point:383.3°Cat760mmHg
Flash Point:185.6°C
Density:1.131g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:207.08954328
Heavy Atom Count:15
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)OC)NC(=O)C1=CC=CC=C1

Technology Process of Methyl 2-benzamidopropanoate

There total 11 articles about Methyl 2-benzamidopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 67-56-1
methanol

: 55405-89-5
N-(1-formylethyl)benzamide

: (2R)-2-(N-benzoylamino)-1,1-dimethoxypropane

: 1108739-07-6
(2S)-2-(N-benzoylamino)-1,1-dimethoxypropane

: 7260-27-7,38767-73-6
(R)-N-benzoylalanine methyl ester

Guidance literature:: With N-iodo-succinimide; copper(II) bis(trifluoromethanesulfonate); (4R,4'R)-2,2'-(propane-2,2'diyl)bis(4-phenyl-4,5-dihydrooxazole); at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction;
DOI:10.1002/anie.200804188

Reference yield:

: 7244-67-9,38767-73-6
methyl N-benzoylalaninate

: 7244-67-9,38767-73-6
N-benzoyl-L-alanine methyl ester

: 7260-27-7,38767-73-6
(R)-N-benzoylalanine methyl ester

Guidance literature:: methyl N-benzoylalaninate; With Mesityl-Li; In tetrahydrofuran; pentane; for 1h;

With 1-[5'-toluenesulfonyl-2'-(methylamino)phenyl]-1,2,3,4-tetrahydroisoquinoline; In tetrahydrofuran; pentane; at -78 - -20 ℃; Title compound not separated from byproducts;
DOI:10.1021/jo990897m

Reference yield:

: 67-56-1
methanol

: 51127-13-0,71963-72-9,87480-74-8,13302-43-7
2-phenyl-4-methyl-4H-oxazolin-5-one

: 7244-67-9,38767-73-6
N-benzoyl-L-alanine methyl ester

: 7260-27-7,38767-73-6
(R)-N-benzoylalanine methyl ester

Guidance literature:: With planar-chiral DMAP-ferrocene derivative; benzoic acid; In toluene; for 48h; Product distribution; Ambient temperature; methanolysis of azlactones dynamic kinetic resolution of azlactones; enantiomeric excess; solvent effect on enantioselectivity; reaction with other alcohols; effect of steric factors on enantioselectivity;
DOI:10.1021/jo9803380