3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran

Base Information

• Chemical Name: 3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran
• CAS No.: 89100-09-4
• Molecular Formula: C14H16O2
• Molecular Weight: 216.28
• DSSTox Substance ID: DTXSID90527938
• Mol file: 89100-09-4.mol

Synonyms:89100-09-4;3-(4-methoxybenzyl)-2,4-dimethylfuran;3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran;DTXSID90527938

Chemical Property of 3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 216.115029749
• Heavy Atom Count: 16
• Complexity: 209

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=COC(=C1CC2=CC=C(C=C2)OC)C

Technology Process of 3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran

There total 2 articles about 3-[(4-Methoxyphenyl)methyl]-2,4-dimethylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

4-(4-Methoxy-phenyl)-3-(2-methyl-oxiranyl)-butan-2-one (89100-05-0) → 3-(4-Methoxy-benzyl)-2,4-dimethyl-furan (89100-09-4)

Guidance literature:

With hydrogenchloride; In methanol; at 65 ℃; for 6h;

DOI:10.1055/s-1983-30598

Reference yield:

2-Methyl-3-(4-methoxybenzyl)-4-oxo-1-penten (67935-55-1) → 3-(4-Methoxy-benzyl)-2,4-dimethyl-furan (89100-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / m-perbenzoic acid / CH₂Cl₂ / 12 h

2: 64 percent / HCl / methanol / 6 h / 65 °C

With hydrogenchloride; m-perbenzoic acid; In methanol; dichloromethane;

DOI:10.1055/s-1983-30598

Reference yield: 90.0%

methanol (67-56-1) + 3-(4-Methoxy-benzyl)-2,4-dimethyl-furan (89100-09-4) → 2,5-Dimethoxy-3-(4-methoxy-benzyl)-2,4-dimethyl-2,5-dihydro-furan (89100-11-8)

Guidance literature:

With tetraethylammonium perchlorate; for 4h; Ambient temperature; platinum foil electrodes (18.7 mA/cm²);

DOI:10.1055/s-1983-30598

upstream raw materials:

4-(4-Methoxy-phenyl)-3-(2-methyl-oxiranyl)-butan-2-one

2-Methyl-3-(4-methoxybenzyl)-4-oxo-1-penten

Downstream raw materials:

2,5-Dimethoxy-3-(4-methoxy-benzyl)-2,4-dimethyl-2,5-dihydro-furan

4-Hydroxy-2-(p-methoxybenzyl)-3-methyl-2-cyclopentenone