2-(2-Methoxyphenyl)-6-methylchromen-4-one

Base Information

Chemical Name:2-(2-Methoxyphenyl)-6-methylchromen-4-one
CAS No.:89112-85-6
Molecular Formula:C17H14O3
Molecular Weight:266.296
Hs Code.:
DSSTox Substance ID:DTXSID40358996
Wikidata:Q82139963
Metabolomics Workbench ID:74770
ChEMBL ID:CHEMBL334355
Mol file:89112-85-6.mol

Synonyms:2'-methoxy-6-methylflavone;2'MeO6MF

Suppliers and Price of 2-(2-Methoxyphenyl)-6-methylchromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(2-Methoxyphenyl)-6-methylchromen-4-one

Chemical Property:

PSA：39.44000
LogP:3.77700
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:266.094294304
Heavy Atom Count:20
Complexity:401

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3OC

Technology Process of 2-(2-Methoxyphenyl)-6-methylchromen-4-one

There total 8 articles about 2-(2-Methoxyphenyl)-6-methylchromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 88952-34-5
1-(2-hydroxy-5-methylphenyl)-3-(2-methoxyphenyl)propane-1,3-dione

: 89112-85-6
2-(2-methoxy-phenyl)-6-methyl-chromen-4-one

Guidance literature:: With sulfuric acid; In acetic acid; at 80 ℃; for 2h;
DOI:10.1021/jm020839k

Reference yield:

: 88951-97-7
2-acetyl-4-methylphenyl 2-methoxybenzoate

: 89112-85-6
2-(2-methoxy-phenyl)-6-methyl-chromen-4-one

Guidance literature:: With pyridine; potassium hydroxide; hydrogenchloride; Yield given. Multistep reaction; 1) 60 deg C, 2h, 2) glacial acetic acid, reflux, 1h;

Reference yield:

: 1450-72-2
5-methyl-2-hydroxyacetophenone

: 89112-85-6
2-(2-methoxy-phenyl)-6-methyl-chromen-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / pyridine / 0.5 h / 50 °C

2: 76 percent / pyridine; KOH / 1.5 h / 50 °C

3: 96 percent / conc. H₂SO₄ / acetic acid / 2 h / 80 °C

With pyridine; potassium hydroxide; sulfuric acid; In acetic acid; 1: Schotten-Baumann reaction / 2: Baker Venkataraman rearrangement;
DOI:10.1021/jm020839k