1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-

Base Information

Chemical Name:1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-
CAS No.:89144-75-2
Molecular Formula:C16H16N2O
Molecular Weight:252.316
Hs Code.:
DSSTox Substance ID:DTXSID40393504

Synonyms:1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-;89144-75-2;DTXSID40393504;AKOS024286906

Suppliers and Price of 1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-

Chemical Property:

Melting Point:94 °C
Boiling Point:403.6±55.0 °C(Predicted)
PSA：33.62000
Density:1.14±0.1 g/cm3(Predicted)
LogP:2.89830
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:252.126263138
Heavy Atom Count:19
Complexity:315

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NNC(C2)C3=CC=CC=C3

Technology Process of 1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl-

There total 6 articles about 1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 959-23-9
4'-methoxychalcone

: 89144-75-2
3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole

Guidance literature:: With hydrazine hydrate; for 0.25h; Heating;
DOI:10.1021/je00036a038

Reference yield:

: 22966-19-4
trans-4'-methoxychalcone

: 89144-75-2
3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole

Guidance literature:: With hydrazine hydrate; In ethanol; at 80 ℃; for 5h;
DOI:10.1016/j.bmc.2012.08.043

Reference yield:

: 100-52-7
benzaldehyde

: 89144-75-2
3-(4-Methoxy-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 0.5 h / Reflux

2: hydrazine hydrate / ethanol / 5 h / 80 °C

With hydrazine hydrate; In ethanol;
DOI:10.1016/j.bmc.2012.08.043