1-Benzyl-1-phenylhydrazine

Base Information

• Chemical Name: 1-Benzyl-1-phenylhydrazine
• CAS No.: 614-31-3
• Molecular Formula: C13H14N2
• Molecular Weight: 198.268
• Hs Code.: 2928000090
• European Community (EC) Number: 210-377-5
• NSC Number: 7145
• UNII: Q9EG0RBA6B
• DSSTox Substance ID: DTXSID60210320
• Nikkaji Number: J37.724D
• Wikidata: Q72442660
• Mol file: 614-31-3.mol

Synonyms:1-benzyl-1-phenylhydrazine;614-31-3;N-Benzyl-N-phenylhydrazine;1-Benzylphenylhydrazine;Q9EG0RBA6B;NSC 7145;NSC-7145;EINECS 210-377-5;Hydrazine, 1-phenyl-1-(phenylmethyl)-;Benzylphenylhydrazin;n'-phenylhexanehydrazide;Enamine_004985;UNII-Q9EG0RBA6B;1-benzyl-1-phenyl-hydrazine;SCHEMBL544819;DTXSID60210320;NSC7145;HMS1408C13;.ALPHA.-BENZYLPHENYLHYDRAZINE;BBL034708;MFCD00059186;STK500247;AKOS000264774;HYDRAZINE, 1-BENZYL-1-PHENYL-;IDI1_007572;AS-58798;1-PHENYL-1-(PHENYLMETHYL)HYDRAZINE;B1157;CS-0454206;FT-0600566;EN300-03635;D88762;A833223;W-109575;F1905-7118

Chemical Property of 1-Benzyl-1-phenylhydrazine

Chemical Property:

• Melting Point: 164-166℃
• Refractive Index: 1.6180-1.6210
• Boiling Point: 346.6 °C at 760 mmHg
• PKA: 5.21±0.10(Predicted)
• Flash Point: 186.3 °C
• PSA: 29.26000
• Density: 1.13 g/cm³
• LogP: 3.26720
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 198.115698455
• Heavy Atom Count: 15
• Complexity: 169

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Benzyl-1-phenylhydrazine ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN(C2=CC=CC=C2)N

Technology Process of 1-Benzyl-1-phenylhydrazine

There total 29 articles about 1-Benzyl-1-phenylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzyl bromide (100-39-0) + phenylhydrazine (100-63-0) → N-benzyl-N-phenylhydrazine (614-31-3)

Guidance literature:

With sodium hydrogencarbonate; In water; for 3h; Reflux; Inert atmosphere;

DOI:10.24820/ark.5550190.p010.543

Reference yield: 96.0%

2-(N-benzyl-anilino)-isoindoline-1,3-dione (530740-37-5) → N-benzyl-N-phenylhydrazine (614-31-3)

Guidance literature:

With hydrazine hydrate; In ethanol; Heating;

DOI:10.1081/SCC-120015563

Reference yield: 88.0%

benzyl chloride (100-44-7) + phenylhydrazine (100-63-0) → N-benzyl-N-phenylhydrazine (614-31-3)

Guidance literature:

With sodium hydroxide; In toluene; Reagent/catalyst; Inert atmosphere; Reflux;

upstream raw materials:

benzyl chloride

2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione

benzyl bromide

tert-butyl 2-phenylhydrazine-1-carboxylate

Downstream raw materials:

4-methyl-benzaldehyde-(benzyl-phenyl-hydrazone)

aniline

1-benzyl-2-benzylidene-1-phenylhydrazine

N,N-dibenzyl-N-phenyl-hydrazinium; chloride

Refernces

• 1、 Zhang, Lei,Chen, Junyu,Chen, Xiahe,Zheng, Xiangyun,Zhou, Jian,Zhong, Tianshuo,Chen, Zhiwei,Yang, Yun-Fang,Jiang, Xinpeng,She, Yuan-Bin,Yu, Chuanming. "Rh(iii)-catalyzed, hydrazine-directed C-H functionalization with 1-alkynylcyclobutanols: A new strategy for 1: H -indazoles". supporting information. p. 7415 - 7418. Retrieved 2020/07/15.
• 2、 Christoffers, Jens,Dierks, Anna,Fliegel, Lukas,Schmidtmann, Marc. "Preparation of Hexahydrocarbazole Derivatives by Reductive Indolization". . p. 7164 - 7175. Retrieved 2020/11/30.