1(4H)-Pyridinecarboxylic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethenyl]-, 2,2,2-trichloroethyl ester

Base Information

• Chemical Name: 1(4H)-Pyridinecarboxylic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethenyl]-, 2,2,2-trichloroethyl ester
• CAS No.: 89318-28-5
• Molecular Formula: C₂₂H₂₈Cl₃NO₃Si
• Molecular Weight: 488.914
• Mol file: 89318-28-5.mol

Synonyms:

Chemical Property of 1(4H)-Pyridinecarboxylic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethenyl]-, 2,2,2-trichloroethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1(4H)-Pyridinecarboxylic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethenyl]-, 2,2,2-trichloroethyl ester

There total 3 articles about 1(4H)-Pyridinecarboxylic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenylethenyl]-, 2,2,2-trichloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine (110-86-1) → 4-[(E)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-vinyl]-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester (89318-28-5)

Guidance literature:

Multi-step reaction with 2 steps

2: acetonitrile

In acetonitrile;

DOI:10.1016/S0040-4039(00)88414-2

Reference yield:

tert-butyldimethyl(1-phenylvinyloxy)silane (66324-10-5) + 1-(2,2,2-Trichloro-ethoxycarbonyl)-pyridinium; chloride (66531-22-4) → 4-[(E)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-vinyl]-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester (89318-28-5)

Guidance literature:

In acetonitrile; Yield given;

DOI:10.1016/S0040-4039(00)88414-2

Reference yield:

pyridine (110-86-1) + tert-butyldimethyl(1-phenylvinyloxy)silane (66324-10-5) + 2,2,2-Trichloroethyl chloroformate (17341-93-4) → 4-[(E)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-vinyl]-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester (89318-28-5)

Guidance literature:

Yield given. Multistep reaction; 1.) CH₂Cl₂, 2.) CH₂Cl₂;

upstream raw materials:

pyridine

tert-butyldimethyl(1-phenylvinyloxy)silane

2,2,2-Trichloroethyl chloroformate

1-(2,2,2-Trichloro-ethoxycarbonyl)-pyridinium; chloride

Downstream raw materials:

4-(2-Oxo-2-phenyl-ethyl)-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester

1-phenyl-2-(4-pyridinyl)ethanone