3-(2-Fluorophenyl)pyridine

Base Information

Chemical Name:3-(2-Fluorophenyl)pyridine
CAS No.:89346-49-6
Molecular Formula:C11H8FN
Molecular Weight:173.19
Hs Code.:
DSSTox Substance ID:DTXSID00533560
Wikidata:Q82406942

Synonyms:3-(2-fluorophenyl)pyridine;89346-49-6;Pyridine, 3-(2-fluorophenyl)-;SCHEMBL2650329;DTXSID00533560;OFVMMLBVGWZEHK-UHFFFAOYSA-N

Suppliers and Price of 3-(2-Fluorophenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(2-Fluorophenyl)pyridine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:173.064077422
Heavy Atom Count:13
Complexity:160

Purity/Quality:: 95-99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CN=CC=C2)F

Technology Process of 3-(2-Fluorophenyl)pyridine

There total 6 articles about 3-(2-Fluorophenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 107-11-9,30551-89-4
1-amino-2-propene

: 75321-85-6
2-(2-fluorophenyl)acetaldehyde

: 89346-49-6
3-(2-fluorophenyl)pyridine

Guidance literature:: With oxygen; sodium acetate; palladium diacetate; tricyclohexylphosphine; In dimethyl sulfoxide; at 100 ℃; for 5h;
DOI:10.1002/adsc.201500685

Reference yield: 63.0%

: 1120-90-7
3-iodopyridine

: 1993-03-9
o-fluorophenylboronic acid

: 89346-49-6
3-(2-fluorophenyl)pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; toluene; at 100 ℃; for 1h; Inert atmosphere; Microwave irradiation;

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 462-06-6
fluorobenzene

: 89346-49-6
3-(2-fluorophenyl)pyridine

Guidance literature:: fluorobenzene; With n-butyllithium; potassium tert-butylate; In 2-methyltetrahydrofuran; hexane; at -40 ℃; Inert atmosphere; Flow reactor;

With zinc(II) chloride; In 2-methyltetrahydrofuran; hexane; Inert atmosphere; Flow reactor;

3-Bromopyridine; With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); In 2-methyltetrahydrofuran; hexane; at 60 ℃; under 258.581 Torr; regioselective reaction; Sonication; Inert atmosphere;
DOI:10.1002/anie.201605584