2-Bromothiazole-5-carboxylic acid

Base Information

Chemical Name:2-Bromothiazole-5-carboxylic acid
CAS No.:54045-76-0
Molecular Formula:C4H2BrNO2S
Molecular Weight:208.035
Hs Code.:29341000
European Community (EC) Number:626-804-7
DSSTox Substance ID:DTXSID80376811
Nikkaji Number:J2.978.027G
Wikidata:Q72512880
Mol file:54045-76-0.mol

Synonyms:54045-76-0;2-Bromothiazole-5-carboxylic acid;2-Bromo-5-thiazolecarboxylic acid;2-bromo-1,3-thiazole-5-carboxylic Acid;2-Bromo-5-thiazolecarboxylicacid;5-Thiazolecarboxylic acid, 2-bromo-;MFCD04115730;2-bromo-thiazole-5-carboxylic acid;2-Bromo-thiazole-5-carboxylicacid;SCHEMBL324369;2-Bromothiazole-5-carboxylicacid;DTXSID80376811;2-BROMO-5-CARBOXYTHIAZOLE;BESGTWHUMYHYEQ-UHFFFAOYSA-N;2-Bromo-thiazol-5-carboxylic acid;CS-D0331;BBL010885;CL2509;STK651471;AKOS005257210;AC-3604;FS-1427;PB12322;2-Bromothiazole-5-carboxylic acid, 97%;SY006695;A7860;AM20100332;B4329;FT-0640216;EN300-102252;J-508553;Z1269156140

Suppliers and Price of 2-Bromothiazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromothiazole-5-carboxylic acid
10g
$ 580.00

TRC
2-Bromothiazole-5-carboxylic acid
1g
$ 120.00

TCI Chemical
2-Bromothiazole-5-carboxylic Acid >97.0%(GC)(T)
5g
$ 182.00

TCI Chemical
2-Bromothiazole-5-carboxylic Acid >97.0%(GC)(T)
1g
$ 60.00

SynQuest Laboratories
2-Bromo-1,3-thiazole-5-carboxylic acid 97%
250 mg
$ 15.00

SynQuest Laboratories
2-Bromo-1,3-thiazole-5-carboxylic acid 97%
1 g
$ 30.00

SynQuest Laboratories
2-Bromo-1,3-thiazole-5-carboxylic acid 97%
5 g
$ 65.00

Sigma-Aldrich
2-Bromothiazole-5-carboxylic acid 97%
5g
$ 325.00

Sigma-Aldrich
2-Bromothiazole-5-carboxylic acid 97%
1g
$ 81.80

Medical Isotopes, Inc.
2-Bromo-5-thiazolecarboxylicacid 97%
1 g
$ 699.00

Total 89 raw suppliers

Chemical Property of 2-Bromothiazole-5-carboxylic acid

Chemical Property:

Appearance/Colour:WHITE TO BROWN POWDER, CRYSTALS OR CRYSTALLINE POWDER AND/OR CHUNKS
Vapor Pressure:1.69E-05mmHg at 25°C
Melting Point:182 °C (dec.)
Boiling Point:350 °C at 760 mmHg
PKA:2.52±0.10(Predicted)
Flash Point:165.5 °C
PSA：78.43000
Density:2.062 g/cm³
LogP:1.60380
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:206.89896
Heavy Atom Count:9
Complexity:132

Purity/Quality:

98%, ^*data from raw suppliers

2-Bromothiazole-5-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 43
Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(SC(=N1)Br)C(=O)O
Uses 2-Bromothiazole-5-carboxylic acid is used as a reagent to synthesize azole-based protein kinase B inhibitors, some of which have anti-cancer properties.

Technology Process of 2-Bromothiazole-5-carboxylic acid

There total 3 articles about 2-Bromothiazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 41731-83-3
ethyl 2-bromo-1,3-thiazole-5-carboxylate

: 54045-76-0
2-bromo-thiazole-5-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; at 0 - 10 ℃; for 1h;

Reference yield: 96.0%

: 54045-74-8
methyl 2-bromo-1,3-thiazole-5-carboxylate

: 54045-76-0
2-bromo-thiazole-5-carboxylic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; methanol; for 0.0833333h;

Reference yield: 79.0%

: ethyl 2-bromothiazole-5-carboxylate hydrochloride

: 54045-76-0
2-bromo-thiazole-5-carboxylic acid

Guidance literature:: ethyl 2-bromothiazole-5-carboxylate hydrochloride; With sodium hydroxide; In methanol; for 3h;

With hydrogenchloride; In methanol;