Benzaldehyde, 4-hydroxy-2-nitro-

Base Information

• Chemical Name: Benzaldehyde, 4-hydroxy-2-nitro-
• CAS No.: 90151-04-5
• Molecular Formula: C7H5NO4
• Molecular Weight: 167.121
• Hs Code.: 2913000090
• Mol file: 90151-04-5.mol

Synonyms:3-nitro-4-hydroxybenzaldehyde;2-Nitro-4-hydroxy-benzaldehyd;Benzaldehyde, 4-hydroxy-2-nitro-;2-nitro-4-hydroxybenzaldehyde;4-hydroxy-2-nitro-benzaldehyde;Benzaldehyde,4-hydroxy-2-nitro;4-Hydroxy-2-nitro-benzaldehyd;

Chemical Property of Benzaldehyde, 4-hydroxy-2-nitro-

Chemical Property:

• Melting Point: 136-137 °C
• Boiling Point: 350.2±32.0 °C(Predicted)
• PKA: 6.21±0.10(Predicted)
• PSA: 83.12000
• Density: 1.500±0.06 g/cm3(Predicted)
• LogP: 1.63610
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Hydroxy-2-nitrobenzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzaldehyde, 4-hydroxy-2-nitro-

There total 8 articles about Benzaldehyde, 4-hydroxy-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-hydroxy-2-nitrobenzaldehyde (90151-04-5)

Guidance literature:

With benzyltriphenylphosphonium nitrate; Methanesulfonic anhydride; at 20 ℃; for 0.333333h;

DOI:10.1080/10426500490274655

Reference yield: 61.0%

4-methoxy-2-nitro-benzaldehyde (22996-21-0) → 4-hydroxy-2-nitrobenzaldehyde (90151-04-5)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 4.5h;

Reference yield: 17.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-hydroxy-3-nitrobenzaldehyde (3011-34-5) + 4-hydroxy-2-nitrobenzaldehyde (90151-04-5)

Guidance literature:

With Nitrogen dioxide; for 12h; under 225.02 Torr;

DOI:10.1021/jo00122a031

upstream raw materials:

chloroform

meta-nitrophenol

α,α-Dibrom-2-nitro-4-acetoxy-toluol

4-hydroxy-benzaldehyde

Downstream raw materials:

ethyl 4-(3-nitro-4-formylphenyl)oxybutanoate

4-benzyloxy-2-nitrobenzaldehyde

2-nitro-4-(2-piperidin-1-ylethoxy)benzaldehyde

2,β-Dinitro-4-benzyloxy-styrol

Refernces

• 1、 Meng, Ge,Zheng, Mei-Lin,Zheng, A-Qun,Wang, Mei,Shi, Juan. "The novel usage of thiourea nitrate in aryl nitration". . p. 87 - 89. Retrieved 2014/02/14.
• 2、 Hajipour, Abdol Reza,Ruoho, Arnold E.. "Nitric acid in the presence of P2O5 supported on silica gel - A useful reagent for nitration of aromatic compounds under solvent-free conditions". . p. 8307 - 8310. Retrieved 2007/10/03.