N-(2-iodophenyl)-N-methylacetamide

Base Information

Chemical Name:N-(2-iodophenyl)-N-methylacetamide
CAS No.:90585-26-5
Molecular Formula:C9H10INO
Molecular Weight:275.089
Hs Code.:
DSSTox Substance ID:DTXSID40524452
Nikkaji Number:J848.835E
Wikidata:Q82391328

Synonyms:N-(2-iodophenyl)-N-methylacetamide;90585-26-5;SCHEMBL19155104;DTXSID40524452

Suppliers and Price of N-(2-iodophenyl)-N-methylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(2-iodophenyl)-N-methylacetamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:274.98071
Heavy Atom Count:12
Complexity:172

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(C)C1=CC=CC=C1I

Technology Process of N-(2-iodophenyl)-N-methylacetamide

There total 4 articles about N-(2-iodophenyl)-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 15310-02-8
o-iodobenzanilide

: 74-88-4
methyl iodide

: 90585-26-5
N-(2-iodophenyl)-N-methylacetamide

Guidance literature:: o-iodobenzanilide; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.583333h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.8b02819

Reference yield: 70.0%

: 153704-11-1
N-(2-bromophenyl)-N-methylacetamide

: 90585-26-5
N-(2-iodophenyl)-N-methylacetamide

Guidance literature:: With tributylphosphine; sodium iodide; nickel dibromide; In 1-methyl-pyrrolidin-2-one; at 190 ℃; for 7h; Inert atmosphere; Molecular sieve; Sealed tube;
DOI:10.1039/c2cc30956d

Reference yield:

: 615-43-0
2-iodophenylamine

: 90585-26-5
N-(2-iodophenyl)-N-methylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.02 g / pyridine / CH₂Cl₂ / 12 h / 20 °C

2: 680 mg / NaH / tetrahydrofuran; various solvent(s) / 21 h / 20 °C

With pyridine; sodium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol061858h