3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one

Base Information

Chemical Name:3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one
CAS No.:90773-05-0
Molecular Formula:C10H9ClN2O2
Molecular Weight:224.6437
Hs Code.:
NSC Number:207120
DSSTox Substance ID:DTXSID00429611

Synonyms:NSC207120;90773-05-0;DTXSID00429611;NSC-207120;3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one

Suppliers and Price of 3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one

Chemical Property:

Vapor Pressure:0.000311mmHg at 25°C
Boiling Point:320.8°Cat760mmHg
Flash Point:147.8°C
Density:1.36g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:224.0352552
Heavy Atom Count:15
Complexity:262

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(=O)N1N=CC2=CC=C(C=C2)Cl
Isomeric SMILES:C1COC(=O)N1/N=C/C2=CC=C(C=C2)Cl

Technology Process of 3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one

There total 2 articles about 3-{[(E)-(4-chlorophenyl)methylidene]amino}-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 109-84-2
2-hydroxyethylhydrazine

: 104-88-1
4-chlorobenzaldehyde

: 616-38-6
carbonic acid dimethyl ester

: 90773-05-0
3-[((4-chlorophenyl)methylene)amino]-2-oxazolidinone

Guidance literature:: 2-hydroxyethylhydrazine; carbonic acid dimethyl ester; With sodium; In methanol; Inert atmosphere; Reflux;

4-chlorobenzaldehyde; With toluene-4-sulfonic acid; In toluene; for 8h; Inert atmosphere; Reflux;
DOI:10.1021/acs.joc.9b01163

Reference yield:

: 80-65-9
3-amino-2-oxazolidinone

: 104-88-1
4-chlorobenzaldehyde

: 90773-05-0
3-[((4-chlorophenyl)methylene)amino]-2-oxazolidinone

Guidance literature:: DOI:10.1021/jm00333a033

Reference yield: 80.0%

: 75-30-9
2-iodo-propane

: 90773-05-0
3-[((4-chlorophenyl)methylene)amino]-2-oxazolidinone

: 3-[1-(1-(4-chlorophenyl)-2-methyl)propyl]amino-2-oxazolidinone

Guidance literature:: With iron(II) triflate; triethyl borane; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; oxygen; In hexane; dichloromethane; ethylene glycol; at 20 ℃; for 15h; Molecular sieve; Inert atmosphere;
DOI:10.1021/acs.joc.9b01163