1-(Butoxymethyl)-4-methoxybenzene

Base Information

• Chemical Name: 1-(Butoxymethyl)-4-methoxybenzene
• CAS No.: 5333-52-8
• Molecular Formula: C12H18O2
• Molecular Weight: 194.274
• NSC Number: 2415
• DSSTox Substance ID: DTXSID60277458
• Nikkaji Number: J516.144D
• Wikidata: Q82008631
• Mol file: 5333-52-8.mol

Synonyms:1-(butoxymethyl)-4-methoxybenzene;5333-52-8;NSC2415;4-(Butoxymethyl)anisole;SCHEMBL15233070;DTXSID60277458;NSC 2415;NSC-2415;4-Methoxybenzyl alcohol, n-butyl ether;4-(BUTOXYMETHYL)-1-METHOXYBENZENE

Chemical Property of 1-(Butoxymethyl)-4-methoxybenzene

Chemical Property:

• Vapor Pressure: 0.0182mmHg at 25°C
• Boiling Point: 262°Cat760mmHg
• Flash Point: 91.2°C
• Density: 0.961g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 194.130679813
• Heavy Atom Count: 14
• Complexity: 128

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCOCC1=CC=C(C=C1)OC

Technology Process of 1-(Butoxymethyl)-4-methoxybenzene

There total 15 articles about 1-(Butoxymethyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-methoxy-benzaldehyde (123-11-5) + butan-1-ol (71-36-3) → butyl (4-methoxyphenyl)methyl ether (5333-52-8)

Guidance literature:

With [(C₆H₆)(PCy₃)(CO)RuH]⁺*BF₄^?; water; hydrogen; In toluene; at 110 ℃; for 12h; under 760.051 Torr; Reagent/catalyst; chemoselective reaction; Catalytic behavior; Glovebox; Schlenk technique; Green chemistry;

DOI:10.1021/acs.orglett.5b00553

Reference yield: 97.0%

4-Methoxybenzyl alcohol (105-13-5) + butan-1-ol (71-36-3) → butyl (4-methoxyphenyl)methyl ether (5333-52-8)

Guidance literature:

With ferric hydrogen sulphate; at 20 - 90 ℃; for 0.25h;

DOI:10.1007/s11164-015-2098-y

Reference yield: 82.0%

(4-methoxy-benzyl)-trimethyl-silane (17988-20-4) + butan-1-ol (71-36-3) → butyl (4-methoxyphenyl)methyl ether (5333-52-8)

Guidance literature:

With pyridine; sodium persulfate; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; at 20 ℃; for 8h; Inert atmosphere; Irradiation;

upstream raw materials:

p-methoxybenzyl chloride

sodium butanolate

4-Methoxybenzyl alcohol

butan-1-ol

Downstream raw materials:

butyl 4-methoxybenzoate

butyl (tert-butylperoxy)(4-methoxyphenyl)methyl ether