2-Amino-2-methylpropyl hydrogen sulfate

Base Information

• Chemical Name: 2-Amino-2-methylpropyl hydrogen sulfate
• CAS No.: 927-82-2
• Molecular Formula: C4H11NO4S
• Molecular Weight: 169.202
• European Community (EC) Number: 653-847-9
• NSC Number: 159057
• DSSTox Substance ID: DTXSID10303559
• Nikkaji Number: J2.890.753B
• Mol file: 927-82-2.mol

Synonyms:2-amino-2-methylpropyl hydrogen sulfate;927-82-2;(2-amino-2-methylpropyl) hydrogen sulfate;NSC159057;(2-amino-2-methylpropoxy)sulfonic acid;DTXSID10303559;RGXZRDJYNDJZBY-UHFFFAOYSA-N;AC8420;MFCD00087342;2-amino-2-methylpropyl hydrogensulfate;AKOS024333855;NSC-159057;SY263598;2-AMINO-2-METHYL-1-PROPANOL HYDROGEN SULFATE

Chemical Property of 2-Amino-2-methylpropyl hydrogen sulfate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.373g/cm³
• XLogP3: -3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 169.04087901
• Heavy Atom Count: 10
• Complexity: 190

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(COS(=O)(=O)O)N

Technology Process of 2-Amino-2-methylpropyl hydrogen sulfate

There total 2 articles about 2-Amino-2-methylpropyl hydrogen sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Amino-2-methyl-1-propanol (124-68-5) → 2-amino-2-methylpropyl hydrogensulfate (927-82-2)

Guidance literature:

With sulfuric acid; In water; at 50 - 120 ℃; for 3h; Product distribution / selectivity;

Reference yield: 100.0%

→ 2-amino-2-methylpropyl hydrogensulfate (927-82-2)

Guidance literature:

Reference yield: 61.0%

carbon disulfide (75-15-0,12122-00-8) + 2-amino-2-methylpropyl hydrogensulfate (927-82-2) → 5,5-dimethylthiazolidine-2-thione (64050-49-3) + 4,4-dimethyloxazolidine-2-thione (54013-55-7) + 4,4-dimethyl-1,3-thiazolidine-2-thione (1908-88-9)

Guidance literature:

With potassium hydroxide; In water; at 80 ℃; for 3.5h;

DOI:10.1016/j.tet.2011.08.023

upstream raw materials:

2-Amino-2-methyl-1-propanol

Downstream raw materials:

2,2-dimethylaziridine

4,4-dimethyl-N-phenyl-4,5-dihydrothiazol-2-amine

1,1-dimethyl-2-(phenylthio)ethylamine

5,5-dimethylthiazolidine-2-thione

Refernces

• 1、 Liu, Jingbo,Li, Fengyun,Wang, Yuanhong,Zhang, Haoxuan,Dong, Jingyue,Sun, Pengwei,Li, Yuxin,Li, Zhengming. "Synthesis, biological activities and 3D-QSAR studies of (R)-2-phenyl-4,5-dihydrothiazole-4-carboxamide derivatives containing a sulfur ether moiety". supporting information. p. 668 - 671. Retrieved 2018/11/27.
• 2、 Solovyov, Igor,Dar'in, Dmitry,Krasavin, Mikhail. "Convenient Approach to 2-Substituted (Thio)morpholin-3-ones from α-Diazoacetates via X-H Carbene Insertion – Lactamization Sequence". . p. 7432 - 7438. Retrieved 2019/11/28.