4-Nitrophenyl (quinolin-3-yl)methyl carbonate

Base Information

Chemical Name:4-Nitrophenyl (quinolin-3-yl)methyl carbonate
CAS No.:918440-74-1
Molecular Formula:C17H12N2O5
Molecular Weight:324.293
Hs Code.:
DSSTox Substance ID:DTXSID20582454
Wikidata:Q82473890

Synonyms:918440-74-1;4-Nitrophenyl (quinolin-3-ylmethyl) carbonate;4-Nitrophenyl (quinolin-3-yl)methyl carbonate;DTXSID20582454

Suppliers and Price of 4-Nitrophenyl (quinolin-3-yl)methyl carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 4-Nitrophenyl (quinolin-3-yl)methyl carbonate

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:324.07462149
Heavy Atom Count:24
Complexity:445

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C=N2)COC(=O)OC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 4-Nitrophenyl (quinolin-3-yl)methyl carbonate

There total 2 articles about 4-Nitrophenyl (quinolin-3-yl)methyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13669-42-6
3-quinolylcarboxaldehyde

: 918440-74-1
4-nitrophenyl (quinolin-3-ylmethyl) carbonate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium borohydride / tetrahydrofuran; ethanol / cooling

2: 219 mg / N-methylmorpholine / 7 h / 20 °C / cooling

With 4-methyl-morpholine; lithium borohydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm060839a

Reference yield:

: 13669-51-7
3-Hydroxymethylquinoline

: 7693-46-1
4-Nitrophenyl chloroformate

: 918440-74-1
4-nitrophenyl (quinolin-3-ylmethyl) carbonate

Guidance literature:: With 4-methyl-morpholine; at 20 ℃; for 7h; cooling;
DOI:10.1021/jm060839a

Reference yield:

: 918440-74-1
4-nitrophenyl (quinolin-3-ylmethyl) carbonate

: quinoline-3-ylmethyl (S)-1-(((R)-3-bromo-4,5-dihydroisoxazol-5-yl)methylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide

2: aq. LiOH / tetrahydrofuran; methanol / 3 h

3: 58 percent / hydroxybenzotriazole hydrate; EDCl / dimethylformamide

With lithium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm060839a