Diethyl oxalacetate sodium salt

Base Information

• Chemical Name: Diethyl oxalacetate sodium salt
• CAS No.: 40876-98-0
• Molecular Formula: C₈H₁₁O₅*Na
• Molecular Weight: 210.162
• Hs Code.: 29183000
• Mol file: 40876-98-0.mol

Synonyms:Butanedioicacid, oxo-, diethyl ester, ion(1-), sodium (9CI);2-(Oxo)succinic acid diethyl estermonosodium salt;Diethyl 2-hydroxy-2-butenedioate sodium salt;Diethyloxalacetate sodium salt;Diethyl oxobutanedioate sodium salt;Diethylsodiooxalacetate;Diethyl sodium oxalacetate;Oxalacetic acid diethyl estersodium salt;Sodium diethyl oxalacetate;Sodium diethyl oxaloacetate;Sodiumdiethyl oxobutanedioate;

Chemical Property of Diethyl oxalacetate sodium salt

Chemical Property:

• Appearance/Colour: beige to light orange crystalline powder
• Melting Point: 188-190 °C
• PSA: 75.66000
• LogP: 0.42700
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: Slightly soluble in water (1.2 g/L) (25°C).

Purity/Quality:

99% ^*data from raw suppliers

Oxalacetic acid diethyl ester sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: T,Xi
• Statements: 45-46-48/20/21/22-36-36/38
• Safety Statements: 26-24/25-45-53

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Dyes, synthesis. Diethyl oxalacetate sodium salt is used in the preparation of oxaloacetic acid. It is also used as an active pharmaceutical intermediate.

Technology Process of Diethyl oxalacetate sodium salt

There total 1 articles about Diethyl oxalacetate sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

ethyl acetate (141-78-6) + oxalic acid diethyl ester (95-92-1) → sodium 1,4-diethoxy-1,4-dioxobut-2-en-2-olate (40876-98-0,88330-76-1,125898-38-6)

Guidance literature:

With sodium ethanolate; In diethyl ether; for 1h; Heating;

Reference yield: 92.0%

3-fluorobenzylidenemalononitrile (2972-71-6) + sodium 1,4-diethoxy-1,4-dioxobut-2-en-2-olate (40876-98-0,88330-76-1,125898-38-6) → ethyl 6-amino-4-(3-fluorophenyl)-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylate

Guidance literature:

With hydrazine hydrate; acetic acid; In ethanol; at 120 ℃; for 1.2h;

DOI:10.1016/j.tetlet.2014.06.077

Reference yield: 89.0%

3-nitrobenzylidenemalononitrile (2826-32-6) + sodium 1,4-diethoxy-1,4-dioxobut-2-en-2-olate (40876-98-0,88330-76-1,125898-38-6) → ethyl 6-amino-4-(3-nitrophenyl)-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylate

Guidance literature:

With hydrazine hydrate; acetic acid; In ethanol; at 120 ℃; for 1.2h;

DOI:10.1016/j.tetlet.2014.06.077

upstream raw materials:

ethyl acetate

oxalic acid diethyl ester

Downstream raw materials:

4,5-dioxo-2-thiophen-2-yl-1-p-tolyl-pyrrolidine-3-carboxylic acid ethyl ester

4,5-dioxo-1-phenyl-2-thiophen-2-yl-pyrrolidine-3-carboxylic acid ethyl ester

diethyl 1,4-cyclohexanedione-2,5-dicarboxylate

5-Hydroxy-1-m-tolyl-1H-pyrazole-3-carboxylic acid ethyl ester

Refernces