2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth oxy]phenyl]propyl ester, (2S)-

Base Information

Chemical Name:2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth oxy]phenyl]propyl ester, (2S)-
CAS No.:919519-64-5
Molecular Formula:C35H48N2O9
Molecular Weight:640.774
Hs Code.:

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-,
(1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth
oxy]phenyl]propyl ester, (2S)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth oxy]phenyl]propyl ester, (2S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth oxy]phenyl]propyl ester, (2S)-

There total 1 articles about 2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[(3-hydroxypropyl)amino]-2-oxoeth oxy]phenyl]propyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 156-87-6
propan-1-ol-3-amine

: 178446-02-1
2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-(((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid

: 919519-64-5
(R)-3-[3,4-dimethoxyphenyl]-1-{3-[2-(3-hydroxypropylamino)-1-oxoethoxy]phenyl}propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

Guidance literature:: With 4-methyl-morpholine; HATU; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

Reference yield: 7.0%

: 244634-31-9
[(1S,2R)-3-[(4-nitrophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]amine hydrochloride

: 919519-64-5
(R)-3-[3,4-dimethoxyphenyl]-1-{3-[2-(3-hydroxypropylamino)-1-oxoethoxy]phenyl}propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

: 530-62-1
1,1'-carbonyldiimidazole

: 1233884-93-9
(S)-{(R)-1-{3-[(10S,11R)-10-benzyl-11-hydroxy-15-methyl-13-(4-nitrophenylsulfonyl)-2,8-dioxo-7-oxa-3,9,13-triazahexadecyloxy]phenyl}-3-(3,4-dimethoxyphenyl)propyl} 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

Guidance literature:: (R)-3-[3,4-dimethoxyphenyl]-1-{3-[2-(3-hydroxypropylamino)-1-oxoethoxy]phenyl}propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate; 1,1'-carbonyldiimidazole; In ethyl acetate; for 2h;

[(1S,2R)-3-[(4-nitrophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]amine hydrochloride; In ethyl acetate; for 22h; Reflux;