Benzenebutanol, 4-(phenoxymethyl)-, 1-formate

Base Information

• Chemical Name: Benzenebutanol, 4-(phenoxymethyl)-, 1-formate
• CAS No.: 920283-16-5
• Molecular Formula: C18H20O3
• Molecular Weight: 284.355
• Mol file: 920283-16-5.mol

Synonyms:

Chemical Property of Benzenebutanol, 4-(phenoxymethyl)-, 1-formate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenebutanol, 4-(phenoxymethyl)-, 1-formate

There total 3 articles about Benzenebutanol, 4-(phenoxymethyl)-, 1-formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-Chlorbutyl)-4-(phenoxymethyl)benzen (101583-36-2) + sodium formate (141-53-7) → formic acid 4-(4-phenoxymethyl-phenyl)-butyl ester (920283-16-5)

Guidance literature:

With tetrabutylammomium bromide; at 125 ℃; for 4h;

Reference yield:

1-Chloro-4-phenylbutane (4830-93-7) → formic acid 4-(4-phenoxymethyl-phenyl)-butyl ester (920283-16-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ZnCl₂ / 0.5 h / 40 °C

1.2: SOCl₂ / 2 h / 50 °C

1.3: K₂CO₃ / acetone / 96 h / Heating

2.1: tetrabutylammonium bromide / 4 h / 125 °C

With tetrabutylammomium bromide; zinc(II) chloride; 1.1: modified Blanc chloromethylation;

Reference yield:

phenol (108-95-2,27073-41-2) → formic acid 4-(4-phenoxymethyl-phenyl)-butyl ester (920283-16-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ZnCl₂ / 0.5 h / 40 °C

1.2: SOCl₂ / 2 h / 50 °C

1.3: K₂CO₃ / acetone / 96 h / Heating

2.1: tetrabutylammonium bromide / 4 h / 125 °C

With tetrabutylammomium bromide; zinc(II) chloride; 1.1: modified Blanc chloromethylation;

upstream raw materials:

1-(4-Chlorbutyl)-4-(phenoxymethyl)benzen

sodium formate

1-Chloro-4-phenylbutane

phenol